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ALDH1A1 抗体

This anti-ALDH1A1 antibody is a 小鼠 单克隆 antibody detecting ALDH1A1 in WB, FACS, IHC (p), IF (p) 和 IF (cc). Suitable for 人.
产品编号 ABIN4906006
发货至: 中国

Quick Overview for ALDH1A1 抗体 (ABIN4906006)

抗原

See all ALDH1A1 抗体
ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This ALDH1A1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

2C2
  • 交叉反应

    纯化方法

    Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

    免疫原

    This ALDH1A1 monoclonal antibody is generated from mouse immunized with ALDH1A1 recombinant protein.

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

    别名

    ALDH1A1

    背景

    Synonyms: ALDC, ALDH1, HEL-9, HEL12, PUMB1, ALDH11, RALDH1, ALDH-E1, HEL-S-53e, Retinal dehydrogenase 1, RALDH 1, ALHDII, Aldehyde dehydrogenase family 1 member A1, Aldehyde dehydrogenase, cytosolic, ALDH1A1.

    Background: ALDH1A1 belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. ALDH1A1 is the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. ALDH1A1 binds free retinal and cellular retinol-binding protein-bound retinal. ALDH1A1 can convert/oxidize retinaldehyde to retinoic acid. ALDH1A1 may have a broader specificity and oxidize other aldehydes in vivo.

    基因ID

    216

    UniProt

    P00352

    途径

    Dopaminergic Neurogenesis
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