Hemoglobin Subunit beta 抗体
Quick Overview for Hemoglobin Subunit beta 抗体 (ABIN4903870)
抗原
See all Hemoglobin Subunit beta (HBB) 抗体适用
宿主
克隆类型
标记
应用范围
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产品特性
- Hemoglobin (Hgb) is coupled to four iron-binding, methene-linked tetrapyrrole rings (heme). The å (16p13.3, 5'-Ω-pseudoz-pseudo å2-pseudo å1-å2-å1-1-3') and (11p15.5) globin loci determine the basic hemoglobin structure. The globin portion of hemoglobin consists of two å chains and two chains arranged in pairs forming a tetramer. Each of the four globin chains covalently associates with a heme group. The bonds between å and chains are weaker than between similar globin chains, thereby forming a cleavage plane that is important for oxygen binding and release. High affinity for oxygen occurs upon relaxation of the å1-2 cleavage plane. When the two å1-2 interfaces are closely bound, hemoglobin has a low affinity for oxygen. Hb A, which contains two å chains plus two chains, comprises 97 % of total circulating hemoglobin. The remaining 3 % of total circulating hemoglobin is comprised of Hb A-2, which consists of two å chains plus two chains, and fetal hemoglobin (Hb F), which consists of two å chains together with two © chains.
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纯化方法
- Affinity purification
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免疫原
- Recombinant protein of human HBB.
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亚型
- IgG
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应用备注
- WB 1:100-1:200 , IHC 1:50-1:100 , FC 1:20-1:50
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C.
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- Hemoglobin Subunit beta (HBB) (Hemoglobin beta (HBB))
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别名
- HBB
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基因ID
- 3043
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UniProt
- P68871
抗原
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