Ubiquitin 抗体
Our Local Distributor
北京 101111
Quick Overview for Ubiquitin 抗体 (ABIN4902435)
抗原
See all Ubiquitin (Ub) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- Ubiquitin is a protein encoded by the UBB gene which is approximately 25,7 kDa. Ubiquitin is localised to the cytoplasm and nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, RET signalling, activated TLR4 signalling and signalling by Notch1. It is one of the most conserved proteins known and has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression and the stress response. Ubiquitin is expressed in the nervous system, blood, liver and pancreas. Mutations in the UBB gene may result in a cleft palate. STJ97742 was developed from clone 5F1 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of ubiquitin.
-
特异性
- Ubiquitin Mouse Monoclonal Antibody (5F1) detects endogenous levels of Ubiquitin
-
产品特性
- Mouse Monoclonal to Ubiquitin.
-
纯化方法
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
-
免疫原
- synthetic peptide derived from Ubiquitin
-
亚型
- IgG1
-
-
-
-
应用备注
-
WB 1:1000-2000
IHC 1:100-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze/thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
-
-
- Ubiquitin (Ub)
-
别名
- Ubiquitin
-
途径
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
抗原
-