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Annexin a1 抗体 (AA 130-180)

The 兔 多克隆 anti-Annexin a1 antibody (ABIN4900980) specifically detects Annexin a1 in WB, ELISA 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN4900980
发货至: 中国
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Quick Overview for Annexin a1 抗体 (AA 130-180) (ABIN4900980)

抗原

See all Annexin a1 (ANXA1) 抗体
Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

适用

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宿主

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克隆类型

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多克隆

标记

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This Annexin a1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 130-180

    原理

    Annexin I is a protein encoded by the ANXA1 gene which is approximately 38,7 kDa. Annexin I is localised to the cell membrane. It is involved in peptide ligand-binding receptors, signalling by GPCR, cytokine signalling in immune system and RET signalling. It is a membrane-localized protein that binds phospholipids and plays an important role in the innate immune response as an effector of glucocorticoid-mediated responses and is a regulator of the inflammatory process. Annexin I is expressed in resting neutrophils. Mutations in the ANXA1 gene may result in hairy cell leukemia. STJ98699 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Annexin I.

    特异性

    The antibody detects endogenous Annexin I.

    产品特性

    Rabbit Polyclonal to Annexin I.

    纯化方法

    The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

    免疫原

    Synthetic peptide from human Annexin I protein.

    亚型

    IgG
  • 应用备注

    WB 1:500-2000
    IHC-P 1:50-300
    ELISA 1:5000-20000

    说明

    Detected in resting neutrophils . Detected in peripheral blood T-cells . Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors . Detected in placenta (at protein level) . Detected in liver.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    PBS,  pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    -20 °C

    储存方法

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • 抗原

    Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

    别名

    Annexin I

    分子量

    38kDa

    基因ID

    301

    UniProt

    P04083

    途径

    Hormone Transport
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