Annexin a1 抗体 (AA 130-180)
Quick Overview for Annexin a1 抗体 (AA 130-180) (ABIN4900980)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 130-180
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原理
- Annexin I is a protein encoded by the ANXA1 gene which is approximately 38,7 kDa. Annexin I is localised to the cell membrane. It is involved in peptide ligand-binding receptors, signalling by GPCR, cytokine signalling in immune system and RET signalling. It is a membrane-localized protein that binds phospholipids and plays an important role in the innate immune response as an effector of glucocorticoid-mediated responses and is a regulator of the inflammatory process. Annexin I is expressed in resting neutrophils. Mutations in the ANXA1 gene may result in hairy cell leukemia. STJ98699 was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This primary antibody detects endogenous Annexin I.
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特异性
- The antibody detects endogenous Annexin I.
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产品特性
- Rabbit Polyclonal to Annexin I.
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纯化方法
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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免疫原
- Synthetic peptide from human Annexin I protein.
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亚型
- IgG
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应用备注
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WB 1:500-2000
IHC-P 1:50-300
ELISA 1:5000-20000 -
说明
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Detected in resting neutrophils . Detected in peripheral blood T-cells . Detected in extracellular vesicles in blood serum from patients with inflammatory bowel disease, but not in serum from healthy donors . Detected in placenta (at protein level) . Detected in liver.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, containing 0.02 % sodium azide as Preservative and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- -20 °C
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储存方法
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- Annexin I
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分子量
- 38kDa
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基因ID
- 301
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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