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L3MBTL2 抗体 (AA 1-230)

There is 1 publication for this product available. The 兔 多克隆 anti-L3MBTL2 antibody is suitable to detect L3MBTL2 in samples from 人. It has been validated for WB 和 IP.
产品编号 ABIN4889662
发货至: 中国
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Quick Overview for L3MBTL2 抗体 (AA 1-230) (ABIN4889662)

抗原

See all L3MBTL2 抗体
L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

适用

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宿主

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克隆类型

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多克隆

标记

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This L3MBTL2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1-230

    原理

    L3MBTL2 antibody (pAb)

    纯化方法

    Unpurified

    免疫原

    This L3MBTL2 antibody was raised against a His-Tagged fusion protein containing amino acids 1-230 of human L3MBTL2.
  • 应用备注

    IP: 10 µL per IP WB: 1:500 - 1:2,000 dilution

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

    储存条件

    -20 °C

    储存方法

    Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

    有效期

    24 months
  • LaFave, Béguelin, Koche, Teater, Spitzer, Chramiec, Papalexi, Keller, Hricik, Konstantinoff, Micol, Durham, Knutson, Campbell, Blum, Shi, Doud, Krivtsov, Chung, Khodos, de Stanchina, Ouerfelli et al.: "Loss of BAP1 function leads to EZH2-dependent transformation. ..." in: Nature medicine, Vol. 21, Issue 11, pp. 1344-9, (2015) (PubMed).

  • 抗原

    L3MBTL2 (Lethal(3) Malignant Brain Tumor-Like Protein 2 (L3MBTL2))

    别名

    L3MBTL2

    背景

    L3MBTL2 (Lethal (3) malignant brain tumor-like 2 protein) is a putative member of the polycomb group family and is the human homolog of Drosophila Sfmbt, critical for Hox gene silencing. L3MBTL2 contains one FCS-type zinc finger and four MBT (malignant brain tumor) repeats. L3MBTL2 associates with chromatin-remodeling complexes and helps inhibit the expression of proteins that trigger the cells into mitosis. L3MBTL2 is a part of a complex involved in the G0 phase of the cell cycle. This complex contains other proteins such as E2F-6, Max or HP1 gamma, and participates in transcriptional repression.

    分子量

    90 kDa

    基因ID

    83746

    NCBI登录号

    NP_113676
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