Prohibitin 2 抗体 (C-Term)
Quick Overview for Prohibitin 2 抗体 (C-Term) (ABIN4889443)
抗原
See all Prohibitin 2 (PHB2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with MBD3 from human, mouse, rat and other species (due to sequence homology)
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纯化方法
- Purified (protein A)
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免疫原
- Synthetic peptide of derived from C terminal part of human Prohibitin-2.
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应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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浓度
- 1 mg/mL
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缓冲液
- Tris 0,1M, glycine 0,1M
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- Prohibitin 2 (PHB2)
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别名
- Prohibitin-2
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背景
- Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
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基因ID
- 11331
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UniProt
- Q99623
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
抗原
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