MBD3 抗体 (C-Term)
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- 抗原 See all MBD3 抗体
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, 猴, Hamster
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MBD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)
- 纯化方法
- Purified (protein A)
- 免疫原
- Synthetic peptide of derived from C terminal part of human MBD3.
- Top Product
- Discover our top product MBD3 Primary Antibody
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- 应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 - 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Must be reconstituted in distilled water.
- 浓度
- 1 mg/mL
- 缓冲液
- Tris 0,1M, glycine 0,1M
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- 有效期
- 6 months
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- 抗原
- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
- 别名
- MBD3 (MBD3 产品)
- 别名
- xmbd3 antibody, MGC69548 antibody, MBD3 antibody, DKFZp459N1635 antibody, AI181826 antibody, AU019209 antibody, methyl-CpG binding domain protein 3 S homeolog antibody, methyl-CpG binding domain protein 3 antibody, mbd3.S antibody, mbd3 antibody, MBD3 antibody, Mbd3 antibody
- 背景
- Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
- 基因ID
- 53615
- UniProt
- O95983
- 途径
- Chromatin Binding
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