MBD3 抗体 (C-Term)
Quick Overview for MBD3 抗体 (C-Term) (ABIN4889329)
抗原
See all MBD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)
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纯化方法
- Purified (protein A)
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免疫原
- Synthetic peptide of derived from C terminal part of human MBD3.
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应用备注
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Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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浓度
- 1 mg/mL
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缓冲液
- Tris 0,1M, glycine 0,1M
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储存条件
- 4 °C/-20 °C
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储存方法
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 6 months
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- MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))
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别名
- MBD3
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背景
- Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.
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基因ID
- 53615
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UniProt
- O95983
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途径
- Chromatin Binding
抗原
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