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KEAP1 抗体 (C-Term)

KEAP1 适用: 人, Pig, 豚鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4889301
发货至: 中国
  • 抗原 See all KEAP1 抗体
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    抗原表位
    • 20
    • 15
    • 15
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 86
    • 57
    • 29
    • 19
    • 18
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    人, Pig, 豚鼠
    宿主
    • 88
    • 7
    • 1
    克隆类型
    • 88
    • 8
    多克隆
    标记
    • 41
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KEAP1 antibody is un-conjugated
    应用范围
    • 83
    • 49
    • 32
    • 26
    • 26
    • 15
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Reacts with KEAP1 from human, pig, guinea pig, sheep and other species (due to 100 % sequence homology)
    纯化方法
    Purified (protein A)
    免疫原
    Synthetic peptide of derived from C terminal part of human KEAP1.
    Top Product
    Discover our top product KEAP1 Primary Antibody
  • 应用备注

    Working dilution: Optimal dilutions should be determined by the end user.
    The following are guidelines only:
    WB(1:500 - 1:200) ICC/ IF(1:200 - 1:1000)

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Must be reconstituted in distilled water.
    浓度
    1 mg/mL
    缓冲液
    Tris 0,1M, glycine 0,1M
    储存条件
    4 °C/-20 °C
    储存方法
    Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
    有效期
    6 months
  • 抗原
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    别名
    KEAP1 (KEAP1 产品)
    别名
    INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
    背景
    Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
    基因ID
    9817
    UniProt
    Q14145
    途径
    Maintenance of Protein Location
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