FOXO 抗体 (N-Term)
This anti-FOXO antibody is a 兔 多克隆 antibody detecting FOXO in ELISA 和 WB. Suitable for Drosophila melanogaster.
Quick Overview for FOXO 抗体 (N-Term) (ABIN4889143)
抗原
See all FOXO 抗体
FOXO
(Forkhead Box, Sub-Group O (FOXO))
适用
Drosophila melanogaster
宿主
兔
克隆类型
多克隆
标记
This FOXO antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB)
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抗原表位
- N-Term
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特异性
- Reacts with the Drosophila melanogaster dFOXO protein
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纯化方法
- Purified (protein A)
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免疫原
- Synthetic peptide derived from Nter domain of the Drosophila dFOXO protein.
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:2000) -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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浓度
- 1 mg/mL
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缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- FOXO (Forkhead Box, Sub-Group O (FOXO))
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别名
- Forkhead Box Protein O (dFOXO)
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背景
- Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor.
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基因ID
- 41709
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UniProt
- Q95V55
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途径
- Cellular Glucan Metabolic Process, Regulation of Cell Size
抗原
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