EGLN3 抗体 (Internal Region)
Quick Overview for EGLN3 抗体 (Internal Region) (ABIN4889115)
抗原
See all EGLN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Reacts with EGLN3 from human, mouse and rat
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纯化方法
- Purified (protein A)
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免疫原
- Synthetic peptide of derived from internal part of human EGLN3.
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC1:100 - 1:1000 WB1:200 - 1:2000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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浓度
- 1 mg/mL
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缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))
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别名
- EGLN3
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背景
- Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site.
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基因ID
- 112399
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UniProt
- Q9H6Z9
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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