SNCA 抗体 (Internal Region, pSer87)
Quick Overview for SNCA 抗体 (Internal Region, pSer87) (ABIN4888969)
抗原
See all SNCA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region, pSer87
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特异性
- Reacts with human Alpha-synuclein pS87
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交叉反应
- 小鼠
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交叉反应 (详细)
- Cross-reacts with rat, mouse and other species due to sequencehomology.
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纯化方法
- Purified (protein A)
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免疫原
- Synthetic peptide derived from internal domain of human Alpha-synuclein containing a phosphoserine at position 87.
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应用备注
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IHC : 1/50 to 1/500 - WB : 1/200 to 1/1000 -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Must be reconstituted in distilled water.
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缓冲液
- Tris 0,1M, glycine 0,1M, sucrose 2 %
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储存条件
- 4 °C/-20 °C
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储存方法
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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有效期
- 24 months
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- SNCA (Synuclein, alpha (SNCA))
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别名
- alpha-Synuclein
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背景
- May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
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UniProt
- P37840
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途径
- Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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