Streptococcus Mutans 抗体
There are 2+ publications for this product available. The 兔 多克隆 anti-Streptococcus Mutans antibody is suitable to detect Streptococcus Mutans in samples from Streptococcus mutans. It has been validated for CLSM, ELISA 和 FACS.
(2 references)
产品编号 ABIN4888516
发货至:
中国
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Quick Overview for Streptococcus Mutans 抗体 (ABIN4888516)
抗原
Streptococcus Mutans
适用
Streptococcus mutans
宿主
兔
克隆类型
多克隆
应用范围
Confocal Laser Scanning Microscopy (CLSM), ELISA, Flow Cytometry (FACS)
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特异性
- Streptococcus mutans, not crossreact against S.oralis ATCC 9811, P.gingivalis, F.nucleatum ATCC 25586
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产品特性
- Streptococcus mutans is a Gram-positive bacterium that lives in the mouth. The bacterium metabolizes different kinds of carbohydrates, creating an acidic environment in the mouth as a result of this process. This acidic environment in the mouth is what causes the tooth decay. S. mutans is considered to be the most cariogenic of all of the oral Streptococci [1]. S. mutans is very important to study, not only because virtually everyone in the world carries it, but also because it has various symptoms that affect our daily lives. As the bacteria develop in the mouth, they cause tooth destruction, impaired speech, difficulty chewing, multiple infections, psychological problems such as low self-esteem, poor social interactions, concentration problems, etc. Though not fatal, tooth decay is one of the most common infectious diseases in humans. Also, cavities caused by the bacteria are the reason for half of all dental visits in the U.S. [2]. The bacteria are most concentrated in the crevices, pits, and fissures that are a normal part of the teeth and surrounding structures. Adults may have a high concentration of S. mutans in their mouths. In contrast, infants and children have a smaller concentration, but they are more vulnerable to the bacteria [3]. One of the important virulence properties of these organisms is their ability to form biofilms known as dental plaque on tooth surfaces. Biofilms are sessile bacterial communities adherent to a surface, and their formation occurs in response to a variety of environmental cues. S. mutans undergoes a developmental program in response to environmental signals that leads to the expression of new phenotypes that distinguish these sessile cells from planktonic cells (4). Microbiological studies have been conducted in particular in patients undergoing treatment for cancer. Radiotherapy-caused hyposalivation may affect the oral microbiota. Variations in quantity, complexity, and quality of the oral microbiota also occur during chemotherapy, leading to a major imbalance of the ecosystem (5).
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纯化方法
- Polyclonal immunoglobulins purified by protein A affinity chromatography
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免疫原
- S. mutans ATCC 25175 1010 cells inactivated in glutaraldehyde 2.5%v/v
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Supplied in 100 mM sodium citrate, 50 mM Tris and 0.05 % v/v glycerol. Neutral pH.
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储存条件
- 4 °C
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: "Fungi and bacteria occupy distinct spatial niches within carious dentin." in: PLoS pathogens, Vol. 20, Issue 5, pp. e1011865, (2024) (PubMed).
: "A dual-species microbial model for studying the dynamics between oral streptococci and periodontal pathogens during biofilm development on titanium surfaces by flow cytometry." in: Research in microbiology, Vol. 167, Issue 5, pp. 393-402, (2017) (PubMed).
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: "Fungi and bacteria occupy distinct spatial niches within carious dentin." in: PLoS pathogens, Vol. 20, Issue 5, pp. e1011865, (2024) (PubMed).
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- Streptococcus Mutans
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物质类
- Bacteria
抗原
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