FCAR 抗体
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北京 101111
Quick Overview for FCAR 抗体 (ABIN4888509)
抗原
See all FCAR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD89 Purified
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特异性
- The mouse monoclonal antibody A59 recognizes an extracellular epitope of CD89, a 55-100 kDa glycoprotein serving as a receptor for IgA and expressed mainly on granulocytes, monocytes and macrophages.
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交叉反应 （详细）
- Human, Non-Human Primates
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Ag8.653 myeloma cells
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亚型
- IgG1 kappa
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anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 22-227) antibody
FCAR 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2F9D8 unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 51-280) antibodyFCAR 适用: 大鼠 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人 WB, FACS, ELISA, IP 宿主: 小鼠 Monoclonal MIP8a unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyKD Validated FCAR 适用: 人 WB 宿主: 兔 Monoclonal 25GB6835 unconjugated Recombinant Antibody
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (APC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 APC
anti-Fc Fragment of IgA, Receptor For (FCAR) antibodyFCAR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 131-230) antibodyFCAR 适用: 人, 大鼠 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 1-287) antibodyFCAR 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) (AA 58-84) antibodyFCAR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgA, Receptor For (FCAR) antibody (FITC)FCAR 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal A59 FITC
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- FCAR (Fc Fragment of IgA, Receptor For (FCAR))
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别名
- CD89
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背景
- Fc fragment of IgA receptor,CD89 (Fc-alpha-R) is a type I transmembrane glycoprotein serving as a receptor for IgA. Soluble CD89 is detectable in serum and retains its IgA binding capacity. For signal transduction the association with FcR gamma chain homodimers is needed. CD89 is expressed on granulocytes, monocytes, macrophages, dendritic cells and myeloid cell lines. Its expression is upregulated in presence of IgA immune complexes, stimulators (such as LPS, PMA), TNF alpha, IL1 beta or GM-CSF, and it is downregulated in presence of TGF beta and suramin. Binding of IgA-opsonized targets to CD89 leads to phagocytic and cytotoxic processes of the immunologic defense.,FcalphaRI, FcAR, CTB-61M7.2
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基因ID
- 2204
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UniProt
- P24071
抗原
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