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ITGA2 抗体 (FITC)

This FITC-conjugated 小鼠 单克隆 anti-ITGA2 antibody (Clone AK7) specifically detects ITGA2 in FACS. The antibody is reactive with 人 和 Non-Human Primate samples.
产品编号 ABIN4888502
发货至: 中国
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Quick Overview for ITGA2 抗体 (FITC) (ABIN4888502)

抗原

See all ITGA2 抗体
ITGA2 (Integrin alpha 2 (ITGA2))

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

  • 108
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单克隆

标记

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This ITGA2 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

AK7
  • 原理

    Anti-Hu CD49b FITC

    特异性

    The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.

    交叉反应 (详细)

    Human, Non-Human Primates

    纯化方法

    Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    Human platelets

    亚型

    IgG1
  • 应用备注

    Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

    限制

    仅限研究用
  • 缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    CD49b

    背景

    Integrin subunit alpha 2,CD49b the integrin alpha 2 chain, associates with CD29 (integrin beta 1 chain) to form VLA-2 integrin complex, which plays a critical role in the processes of lymphocyte adhesion and activation. VLA-2 serves as a receptor for collagen, laminin, and fibronectin and also regulates the extracellular matrix synthesis and organization. CD49b has been used to identify NK cells, and coexpressed with CD223 (LAG-3) it identifies CD4+ T regulatory type 1 cells (Tr1).,ITGA2, VLA-2 alpha, GPIa

    基因ID

    3673

    UniProt

    P17301

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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