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ITGA2 抗体

This anti-ITGA2 antibody is a 小鼠 单克隆 antibody detecting ITGA2 in FACS, WB, ELISA, IP, ICC 和 IHC (fro). Suitable for 人 和 Non-Human Primate.
产品编号 ABIN4888501
发货至: 中国

Quick Overview for ITGA2 抗体 (ABIN4888501)

抗原

See all ITGA2 抗体
ITGA2 (Integrin alpha 2 (ITGA2))

适用

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人, Non-Human Primate

宿主

  • 80
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小鼠

克隆类型

  • 89
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单克隆

标记

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This ITGA2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

AK7
  • 原理

    Anti-Hu CD49b Purified

    特异性

    The mouse monoclonal antibody AK7 recognizes an extracellular epitope of CD49b, a 160-165 kDa alpha subunit of VLA-2 integrin complex expressed on platelets, megakaryocytes, activated T and B cells, monocytes, epithelial cells, endothelial cells and fibroblasts.

    交叉反应 (详细)

    Human, Non-Human Primates

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Human platelets

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.
    Immunohistochemistry: Recommended dilution: 5-10 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • 抗原

    ITGA2 (Integrin alpha 2 (ITGA2))

    别名

    CD49b

    背景

    Integrin subunit alpha 2,CD49b the integrin alpha 2 chain, associates with CD29 (integrin beta 1 chain) to form VLA-2 integrin complex, which plays a critical role in the processes of lymphocyte adhesion and activation. VLA-2 serves as a receptor for collagen, laminin, and fibronectin and also regulates the extracellular matrix synthesis and organization. CD49b has been used to identify NK cells, and coexpressed with CD223 (LAG-3) it identifies CD4+ T regulatory type 1 cells (Tr1).,ITGA2, VLA-2 alpha, GPIa

    基因ID

    3673

    UniProt

    P17301

    途径

    CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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