PVRL1 抗体
Quick Overview for PVRL1 抗体 (ABIN4888494)
抗原
See all PVRL1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD111 Purified
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特异性
- The mouse monoclonal antibody R1.302 recognizes an extracellular epitope on CD111 (also known as Nectin 1), a 75 kDa type I transmembrane glycoprotein broadly expressed on endothelial cells, epithelial cells, neuronal cells, megakaryocytes, and CD34-positive stem cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- NIH/3T3 cells transfected with human CD111
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亚型
- IgG1 kappa
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anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 177-190), (Extracellular) antibody
PVRL1 适用: 人 WB, FACS, IHC, IF, LCI, IC 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 1-352) antibodyPVRL1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 1-352) antibodyPVRL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 31-130) antibodyPVRL1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 33-142) antibodyPVRL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 137-186) antibodyPVRL1 适用: 人, Cow, 犬, 豚鼠, 马, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) antibody (PE)PVRL1 适用: 人 FACS 宿主: 小鼠 Monoclonal R1-302 PE
anti-Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (AA 70-350) antibodyPVRL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
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别名
- CD111
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背景
- Nectin cell adhesion molecule 1,CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells. It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells. CD111 is connected with actin cytoskeleton through afadin. Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.,NECTIN1, ED4, HIgR, HV1S, HVEC, OFC7, PRR1, PVRR, CD111, PVRL1, PVRR1, SK-12, CLPED1
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基因ID
- 5818
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UniProt
- Q15223
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途径
- Cell-Cell Junction Organization
抗原
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