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ZP1 抗体 (N-Term)

This anti-ZP1 antibody is a 兔 多克隆 antibody detecting ZP1 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN4886775
发货至: 中国

Quick Overview for ZP1 抗体 (N-Term) (ABIN4886775)

抗原

See all ZP1 抗体
ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

适用

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人, 大鼠

宿主

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克隆类型

  • 27
多克隆

标记

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This ZP1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 102-139, N-Term

    原理

    Anti-ZP1 Antibody Picoband®

    序列

    HVLEKDGRFH LRVFMEAVLP NGRVDVAQDA TLICPKPD

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ZP1 Antibody Picoband® (ABIN4886775). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human ZP1, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. Gross, M. B. Personal Communication. Baltimore, Md. 6/24/2014. 2. Huang, Hua-Lin, Lv, Chao, Zhao, Ying-Chun, Li, Wen, He, Xue-Mei, Li, Ping, Sha, Ai-Guo, Tian, Xiao, Papasian, Christopher J., Deng, Hong-Wen, Lu, Guang-Xiu, Xiao, Hong-Mei (2014). "Mutant ZP1 in Familial Infertility". New England Journal of Medicine 370 (13): 1220-1226. 3. Rankin, T., Talbot, P., Lee, E., Dean, J. Abnormal zonae pellucidae in mice lacking ZP1 result in early embryonic loss.Development 126: 3847-3855, 1999.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ZP1 (Zona Pellucida Glycoprotein 1 (ZP1))

    别名

    ZP1

    背景

    Synonyms: Zona pellucida sperm-binding protein 1,Zona pellucida glycoprotein 1,Zp-1,Processed zona pellucida sperm-binding protein 1,ZP1,

    Tissue Specificity: Oocytes.

    Background: Zona pellucida sperm-binding protein 1 (ZP1) is a protein that belopngs to the mammalian zona pellucida. The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. Zp1 ensures the structural integrity of the zona pellucida. Mutations in this gene are a cause of oocyte maturation defect and infertility. And this gene is mapped to chromosome 11q12.2.

    分子量

    70 kDa, 100 kDa

    基因ID

    22917

    UniProt

    P60852
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