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VASP 抗体 (N-Term)

VASP 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886759
发货至: 中国
  • 抗原 See all VASP 抗体
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    抗原表位
    • 19
    • 17
    • 15
    • 10
    • 9
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 78-114, N-Term
    适用
    • 135
    • 64
    • 57
    • 11
    • 10
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 115
    • 19
    • 2
    克隆类型
    • 110
    • 26
    多克隆
    标记
    • 78
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This VASP antibody is un-conjugated
    应用范围
    • 103
    • 51
    • 48
    • 26
    • 21
    • 16
    • 14
    • 14
    • 12
    • 11
    • 5
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Vasodilator-stimulated phosphoprotein(VASP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    NFHQWRDARQ VWGLNFGSKE DAAQFAAGMA SALEALE
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Vasodilator-stimulated phosphoprotein(VASP) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: vasodilator-stimulated phosphoprotein
    Protein Name: Vasodilator-stimulated phosphoprotein
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human VASP (78-114aa NFHQWRDARQVWGLNFGSKEDAAQFAAGMASALEALE), different from the related mouse sequence by four amino acids.
    亚型
    IgG
    Top Product
    Discover our top product VASP Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    VASP (Vasodilator-Stimulated phosphoprotein (VASP))
    别名
    VASP (VASP 产品)
    别名
    vasp antibody, MGC80889 antibody, wu:fb23b04 antibody, wu:fk84g05 antibody, zgc:110347 antibody, si:dkey-113g17.1 antibody, si:ch211-202c21.1 antibody, DDBDRAFT_0188463 antibody, DDBDRAFT_0229340 antibody, DDB_0188463 antibody, DDB_0229340 antibody, VASP antibody, vasodilator stimulated phosphoprotein S homeolog antibody, vasodilator stimulated phosphoprotein b antibody, protein enabled antibody, vasodilator-stimulated phosphoprotein antibody, vasodilator stimulated phosphoprotein a antibody, vasodilator stimulated phosphoprotein antibody, vasp.S antibody, vaspb antibody, LOC5573842 antibody, CpipJ_CPIJ004706 antibody, CpipJ_CPIJ004707 antibody, vasP antibody, vasp antibody, VASP antibody, vaspa antibody, Vasp antibody
    背景
    Vasodilator-stimulated phosphoprotein (VASP) is a member of the Ena-VASP protein family. Ena-VASP family members contain an EHV1 N-terminal domain that binds proteins containing E/DFPPPPXD/E motifs and targets Ena-VASP proteins to focal adhesions. In the mid-region of the protein, family members have a proline-rich domain that binds SH3 and WW domain-containing proteins. Their C-terminal EVH2 domain mediates tetramerization and binds both G and F actin. VASP is associated with filamentous actin formation and likely plays a widespread role in cell adhesion and motility. VASP may also be involved in the intracellular signaling pathways that regulate integrin-extracellular matrix interactions. VASP is regulated by the cyclic nucleotide-dependent kinases PKA and PKG.

    Synonyms: VASP | P50552
    基因ID
    7408
    UniProt
    P50552
    途径
    TCR Signaling, Regulation of Actin Filament Polymerization, Tube Formation
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