TLN2 抗体 (Middle Region)
Quick Overview for TLN2 抗体 (Middle Region) (ABIN4886745)
抗原
See all TLN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1787-1822, Middle Region
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原理
- Anti-Talin 2/TLN2 Antibody
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序列
- NPKAQHTHDA ITEAAQLMKE AVDDIMVTLN EAASEV
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Talin 2/TLN2 Antibody (ABIN4886745). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Talin 2.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "The role of talin2 in breast cancer tumorigenesis and metastasis." in: Oncotarget, Vol. 8, Issue 63, pp. 106876-106887, (2017) (PubMed).
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: "The role of talin2 in breast cancer tumorigenesis and metastasis." in: Oncotarget, Vol. 8, Issue 63, pp. 106876-106887, (2017) (PubMed).
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- TLN2 (Talin 2 (TLN2))
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别名
- TLN2
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背景
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Synonyms: Talin-2,TLN2,KIAA0320,
Tissue Specificity: Expressed in small intestine, and at much lower levels in kidney, skeletal muscle, and adipose tissue.
Background: Talin 2 is a protein in humans that is encoded by the TLN2 gene. It belongs to the talin protein family. This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. Talin-2 is expressed at high levels in cardiac muscle and functions to provide linkages between the extracellular matrix and actin cytoskeleton at costamere structures to transduce force laterally.
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分子量
- 271 kDa
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基因ID
- 83660
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UniProt
- Q9Y4G6
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途径
- Cell-Cell Junction Organization, Maintenance of Protein Location
抗原
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