SRI 抗体 (Middle Region)
Quick Overview for SRI 抗体 (Middle Region) (ABIN4886730)
抗原
See all SRI 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 89-116, Middle Region
-
原理
- Anti-SR1/SRI Antibody Picoband®
-
序列
- TMGFNEFKEL WAVLNGWRQH FISFDTDR
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-SR1/SRI Antibody (ABIN4886730). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human SR1, different from the related mouse sequence by one amino acid.
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. "Entrez Gene: SRI sorcin". 2. Meyers, M B, Pickel V M, Sheu S S, Sharma V K, Scotto K W, Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 26411-8. 3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 5927-32. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- SRI (Sorcin (SRI))
-
别名
- SRI
-
背景
-
Synonyms: Sorcin,22 kDa protein,CP-22,CP22,V19,SRI,
Tissue Specificity: Detected in cardiac myocytes.
Background: Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
-
分子量
- 26 kDa
-
基因ID
- 6717
-
UniProt
- P30626
-
途径
- Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
抗原
-