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SRI 抗体 (Middle Region)

This anti-SRI antibody is a 兔 多克隆 antibody detecting SRI in WB. Suitable for 人 和 大鼠.
产品编号 ABIN4886730
发货至: 中国

Quick Overview for SRI 抗体 (Middle Region) (ABIN4886730)

抗原

See all SRI 抗体
SRI (Sorcin (SRI))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This SRI antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 89-116, Middle Region

    原理

    Anti-SR1/SRI Antibody Picoband®

    序列

    TMGFNEFKEL WAVLNGWRQH FISFDTDR

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-SR1/SRI Antibody (ABIN4886730). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human SR1, different from the related mouse sequence by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. "Entrez Gene: SRI sorcin". 2. Meyers, M B, Pickel V M, Sheu S S, Sharma V K, Scotto K W, Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 26411-8. 3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 5927-32.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    SRI (Sorcin (SRI))

    别名

    SRI

    背景

    Synonyms: Sorcin,22 kDa protein,CP-22,CP22,V19,SRI,

    Tissue Specificity: Detected in cardiac myocytes.

    Background: Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alternative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.

    分子量

    26 kDa

    基因ID

    6717

    UniProt

    P30626

    途径

    Transition Metal Ion Homeostasis, Maintenance of Protein Location, Negative Regulation of Transporter Activity
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