Peptide YY 抗体 (Middle Region)
Quick Overview for Peptide YY 抗体 (Middle Region) (ABIN4886709)
抗原
See all Peptide YY (PYY) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 29-64, Middle Region
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原理
- Anti-Peptide YY/PYY Antibody
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序列
- YPAKPEAPGE DASPEELSRY YASLRHYLNL VTRQRY
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Peptide YY/PYY Antibody Picoband® (ABIN4886709). Tested in IF, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of mouse Peptide YY, different from the related human sequence by three amino acids, and identical to the related rat sequence.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Immunofluorescence, 5 μg/mL, Rat
1. Liu C, Aloia T, Adrian T, Newton T, Bilchik A, Zinner M, Ashley S, McFadden D (1996). "Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders". Am Surg 62 (3): 232-6. 2. Taylor IL (March 1985). "Distribution and release of peptide YY in dog measured by specific radioimmunoassay". Gastroenterology 88 (3): 731-7. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Peptide YY (PYY)
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别名
- Pyy
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背景
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Synonyms: Peptide YY ,PYY ,Peptide tyrosine tyrosine,Peptide YY (3-36) ,PYY-II ,Pyy,
Tissue Specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus. .
Background: Peptide YY (PYY), also known as peptide tyrosine tyrosine, is a peptide that in humans is encoded by the PYY gene. This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded preproprotein is proteolytically processed to generate two alternative peptide products that differ in length by three amino acids. These peptides, secreted by endocrine cells in the gut, exhibit different binding affinities for each of the neuropeptide Y receptors. Binding of the encoded peptides to these receptors mediates regulation of pancreatic secretion, gut mobility and energy homeostasis. Rare variations in this gene could increase susceptibility to obesity and elevated serum levels of the encoded peptides may be associated with anorexia nervosa.
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Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
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分子量
- 19 kDa
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基因ID
- 217212
抗原
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