PSMA4 抗体 (Middle Region)
Quick Overview for PSMA4 抗体 (Middle Region) (ABIN4886707)
抗原
See all PSMA4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 84-123, Middle Region
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原理
 - Anti-PSMA4 Antibody Picoband®
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序列
 - NVLTNELRLI AQRYLLQYQE PIPCEQLVTA LCDIKQAYTQ
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交叉反应 (详细)
 - No cross-reactivity with other proteins.
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产品特性
 - Anti-PSMA4 Antibody Picoband® (ABIN4886707). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
 - Immunogen affinity purified.
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免疫原
 - A synthetic peptide corresponding to a sequence in the middle region of human PSMA4, identical to the related mouse and rat sequences.
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亚型
 - IgG
 
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应用备注
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                        Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Groll M, Ditzel L, Löwe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). "Structure of 20S proteasome from yeast at 2.4 A resolution". Nature 386 (6624): 463-71. 2. Tomko RJ, Hochstrasser M (2013). "Molecular architecture and assembly of the eukaryotic proteasome". Annual Review of Biochemistry 82: 415-45. - 
                                            
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
 - 仅限研究用
 
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状态
 - Lyophilized
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溶解方式
 - Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
 - 500 μg/mL
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缓冲液
 - Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
 - Sodium azide
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注意事项
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
 - Avoid repeated freezing and thawing.
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储存条件
 - 4 °C,-20 °C
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储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. 
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- PSMA4 (Proteasome Subunit alpha 4 (PSMA4))
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别名
 - PSMA4
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背景
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Synonyms: Proteasome subunit alpha type-4,3.4.25.1,Macropain subunit C9,Multicatalytic endopeptidase complex subunit C9,Proteasome component C9,Proteasome subunit L,PSMA4,HC9, PSC9,
Background: Proteasome subunit alpha type-4, also known as macropain subunit C9, proteasome component C9, and 20S proteasome subunit alpha-3, is a protein that in humans is encoded by the PSMA4 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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分子量
 - 29 kDa
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基因ID
 - 5685
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UniProt
 - P25789
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途径
 - Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
 
抗原
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