PSMA2 抗体 (Middle Region)
Quick Overview for PSMA2 抗体 (Middle Region) (ABIN4886705)
抗原
See all PSMA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 82-123, Middle Region
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原理
- Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband®
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序列
- DYRVLVHRAR KLAQQYYLVY QEPIPTAQLV QRVASVMQEY T
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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产品特性
- Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband® (ABIN4886705). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PSMA2, identical to the related mouse and rat sequences.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Groll M, Ditzel L, Löwe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). "Structure of 20S proteasome from yeast at 2.4 A resolution". Nature 386 (6624): 463-71. 2. Tomko RJ, Hochstrasser M (2013). "Molecular architecture and assembly of the eukaryotic proteasome". Annual Review of Biochemistry 82: 415-45. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- PSMA2 (Proteasome Subunit alpha 2 (PSMA2))
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别名
- PSMA2
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背景
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Synonyms: Proteasome subunit alpha type-2,3.4.25.1,Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3,PSMA2,HC3, PSC3,
Tissue Specificity: Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Background: Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
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分子量
- 26 kDa
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基因ID
- 5683
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UniProt
- P25787
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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