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PSMA2 抗体 (Middle Region)

This anti-PSMA2 antibody is a 兔 多克隆 antibody detecting PSMA2 in WB. Suitable for 人 和 大鼠.
产品编号 ABIN4886705
发货至: 中国

Quick Overview for PSMA2 抗体 (Middle Region) (ABIN4886705)

抗原

See all PSMA2 抗体
PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PSMA2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 82-123, Middle Region

    原理

    Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband®

    序列

    DYRVLVHRAR KLAQQYYLVY QEPIPTAQLV QRVASVMQEY T

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband® (ABIN4886705). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human PSMA2, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. Groll M, Ditzel L, Löwe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). "Structure of 20S proteasome from yeast at 2.4 A resolution". Nature 386 (6624): 463-71. 2. Tomko RJ, Hochstrasser M (2013). "Molecular architecture and assembly of the eukaryotic proteasome". Annual Review of Biochemistry 82: 415-45.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    PSMA2 (Proteasome Subunit alpha 2 (PSMA2))

    别名

    PSMA2

    背景

    Synonyms: Proteasome subunit alpha type-2,3.4.25.1,Macropain subunit C3,Multicatalytic endopeptidase complex subunit C3,Proteasome component C3,PSMA2,HC3, PSC3,

    Tissue Specificity: Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.

    Background: Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.

    分子量

    26 kDa

    基因ID

    5683

    UniProt

    P25787

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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