PNP 抗体 (Middle Region)
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- 抗原 See all PNP 抗体
- PNP (Purine Nucleoside Phosphorylase (PNP))
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抗原表位
- AA 161-189, Middle Region
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PNP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- 原理
- Anti-Nucleoside phosphorylase/PNP Antibody Picoband®
- 序列
- AMSDAYDRTM RQRALSTWKQ MGEQRELQE
- 交叉反应 （详细）
- No cross-reactivity with other proteins.
- 产品特性
- Anti-Nucleoside phosphorylase/PNP Antibody Picoband® (ABIN4886701). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human PNP, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product PNP Primary Antibody
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anti-Purine Nucleoside Phosphorylase (PNP) (AA 161-189) antibody
PNP 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E5 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 174-283) antibodyPNP 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 68-289) antibodyPNP 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 142-153) antibodyVerified PNP 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 145-178) antibodyPNP 适用: 人 WB 宿主: 兔 Polyclonal RB49601 unconjugated
anti-Purine Nucleoside Phosphorylase (PNP) (AA 1-289) antibodyPNP 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. Williams, S. R., Goddard, J. M., Martin, D. W., Jr. Human purine nucleoside phosphorylase cDNA sequence and genomic clone characterization. Nucleic Acids Res. 12: 5779-5787, 1984. 2. Frecker, M., Dallaire, L., Young, S. R., Chen, G. C. C., Simpson, N. E. Confirmation of regional assignment of nucleoside phosphorylase (NP) on chromosome 14 by gene dosage studies. Hum. Genet. 45: 167-173, 1978. 3. Markert, M. L., Finkel, B. D., McLaughlin, T. M., Watson, T. J., Collard, H. R., McMahon, C. P., Andrews, L. G., Barrett, M. J., Ward, F. E. Mutations in purine nucleoside phosphorylase deficiency. Hum. Mutat. 9: 118-121, 1997. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- PNP (Purine Nucleoside Phosphorylase (PNP))
- 别名
- PNP (PNP 产品)
- 背景
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Synonyms: Purine nucleoside phosphorylase,PNP,2.4.2.1,Inosine phosphorylase,Inosine-guanosine phosphorylase,PNP,NP,
Tissue Specificity: Expressed in red blood cells, overexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology. .
Background: The PNP gene encodes purine nucleoside phosphorylase, an enzyme that catalyzes the reversible phosphorolysis of the purine nucleosides and deoxynucleosides inosine, guanosine, deoxyinosine, and deoxyguanosine. It is presented results from gene dosage studies consistent with assignment of the PNP locus to band 14q13. PNP is expressed in most tissues, with markedly greater expression in lymphoid tissues. Genetic deficiencies of PNP result in severely compromised Tlymphocyte function and neurologic dysfunction.
- 分子量
- 32 kDa
- 基因ID
- 4860
- UniProt
- P00491
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Ribonucleoside Biosynthetic Process, Positive Regulation of Response to DNA Damage Stimulus
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