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ADRP 抗体 (AA 226-418)

This anti-ADRP antibody is a 兔 多克隆 antibody detecting ADRP in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886697
发货至: 中国

Quick Overview for ADRP 抗体 (AA 226-418) (ABIN4886697)

抗原

See all ADRP (PLIN2) 抗体
ADRP (PLIN2) (Perilipin 2 (PLIN2))

适用

  • 111
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  • 2
人, 小鼠, 大鼠

宿主

  • 64
  • 42
  • 5
  • 1

克隆类型

  • 59
  • 53
多克隆

标记

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  • 2
  • 1
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This ADRP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 28
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    • 1
    AA 226-418

    原理

    Anti-ADFP/PLIN2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-ADFP/PLIN2 Antibody Picoband® (ABIN4886697). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human ADFP recombinant protein (Position: K226-Q418). Human ADFP shares 88.4% amino acid (aa) sequence identity with mouse ADFP.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Western blot, 0.1-0.5 μg/mL, Human
    1. Heid, H. W., Schnolzer, M., Keenan, T. W. Adipocyte differentiation-related protein is secreted into milk as a constituent of milk lipid globule membrane. Biochem. J. 320: 1025-1030, 1996. 2. Shaw, C. S., Sherlock, M., Stewart, P. M., Wagenmakers, A. J. M.Adipophilin distribution and colocalisation with lipid droplets in skeletal muscle. Histochem. Cell Biol. 131: 575-581, 2009.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ADRP (PLIN2) (Perilipin 2 (PLIN2))

    别名

    PLIN2

    背景

    Synonyms: Perilipin-2,Adipophilin,Adipose differentiation-related protein,ADRP,PLIN2,ADFP,

    Tissue Specificity: Milk lipid globules.

    Background: Adipose differentiation-related protein, also known as perilipin 2 (PLIN2), ADRP or adipophilin, is a protein which in humans is encoded by the ADFP gene. The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.

    分子量

    48 kDa

    基因ID

    123

    UniProt

    Q99541

    途径

    Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
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