MUT 抗体 (N-Term)
Quick Overview for MUT 抗体 (N-Term) (ABIN4886676)
抗原
See all MUT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-65, N-Term
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原理
- Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband®
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序列
- LHQQQPLHPE WAALAKKQLK GKNPEDLIWH TPE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Methylmalonyl Coenzyme A mutase Antibody Picoband® (ABIN4886676). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MUT, different from the related mouse sequence by one amino acid.
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亚型
- IgG
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anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 32-66) antibody
MUT 适用: 小鼠, 人 WB, IHC (p) 宿主: 兔 Polyclonal RB57882 unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 492-526) antibodyMUT 适用: 小鼠, 人 WB, IF 宿主: 兔 Polyclonal RB57881 unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 1-750) antibodyMUT 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 1-750) antibodyMUT 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 451-750) antibodyMUT 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) (AA 44-93) antibodyMUT 适用: 小鼠, 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methylmalonyl Coenzyme A Mutase (MUT) antibodyKD Validated MUT 适用: 小鼠, 人, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Adjalla, C. E., Hosack, A. R., Gilfix, B. M., Lamothe, E., Sun, S., Chan, A., Evans, S., Matiaszuk, N. V., Rosenblatt, D. S. Seven novel mutations in mut methylmalonic aciduria. Hum. Mutat. 11: 270-274, 1998. 2. Berger, I., Shaag, A., Anikster, Y., Baumgartner, E. R., Bar-Meir, M., Joseph, A., Elpeleg, O. N. Mutation analysis of the MCM gene in Israeli patients with mut(0) disease. Molec. Genet. Metab. 73: 107-110, 2001. 3. Cavicchi, C., Donati, M. A., Funghini, S., la Marca, G., Malvagia, S., Ciani, F., Poggi, G. M., Pasquini, E., Zammarchi, E., Morrone, A. Genetic and biochemical approach to early prenatal diagnosis in a family with mut methylmalonic aciduria. Clin. Genet. 69: 72-76, 2006. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MUT (Methylmalonyl Coenzyme A Mutase (MUT))
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别名
- MUT
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背景
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Synonyms: Methylmalonyl-CoA mutase, mitochondrial,MCM,5.4.99.2 ,Methylmalonyl-CoA isomerase,MUT,
Tissue Specificity: T-cell specific.
Background: Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.
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分子量
- 83 kDa
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基因ID
- 4594
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UniProt
- P22033
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途径
- Monocarboxylic Acid Catabolic Process
抗原
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