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MUC3B 抗体 (C-Term)

The 兔 多克隆 anti-MUC3B antibody is suitable to detect MUC3B in samples from 人. It has been validated for WB.
产品编号 ABIN4886675
发货至: 中国
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Quick Overview for MUC3B 抗体 (C-Term) (ABIN4886675)

抗原

MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

适用

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宿主

  • 21

克隆类型

  • 21
多克隆

标记

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This MUC3B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    原理

    Anti-MUC3/MUC3A/MUC3B Antibody

    序列

    DLNDNTSQAY RDFNKTFWNQ MQKIFADMQG FTFK

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-MUC3/MUC3A/MUC3B Antibody (ABIN4886675). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human MUC3.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

    别名

    MUC3B

    背景

    Synonyms: Mucin-3B ,MUC-3B ,Intestinal mucin-3B ,MUC3B ,

    Tissue Specificity: Fetal and adult small intestine and fetal and adult colon. .

    Background: MUC3 consists of two genes, MUC3A and MUC3B, each encoding membrane-bound mucins possessing 2 epidermal growth factor-like domains. The MUC3 gene is mapped to chromosome 7. It was showed that synthetic peptide-mediated upregulation of MUC3 dramatically inhibited adherence of enteropathogenic E. coli or enterohemorrhage E. coli serotype O157:H7 to HT-29 human intestinal epithelial cells. Peptide stimulation altered expression of a number of transcription factors, including upregulation of SP1, CREB1, and CDX2. These transcription factors bound to consensus sites in the MUC3 promoter upon peptide stimulation and likely mediated MUC3 upregulation.

    分子量

    345 kDa

    基因ID

    4584, 57876

    UniProt

    Q9H195
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