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MGP 抗体 (AA 20-96)

This anti-MGP antibody is a 兔多克隆 antibody detecting MGP in WB 和 IHC. Suitable for 人.

Western blot analysis of MGP expression in JURKAT whole cell lysates ( Lane 1). (MGP 抗体 (AA 20-96))

MGP was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- MGP Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (MGP 抗体 (AA 20-96))

2 images

产品编号 ABIN4886666

发货至: 中国

Quick Overview for MGP 抗体 (AA 20-96) (ABIN4886666)

抗原

See all MGP 抗体

MGP (Matrix Gla Protein (MGP))

适用

26
24
17
3
3
3
1
1

人

宿主

兔

克隆类型

多克隆

标记

34
10
6
1
1
1
1
1
1
1
1

This MGP antibody is un-conjugated

应用范围

46
37
25
20
9
4
3
3
2
1

Western Blotting (WB), Immunohistochemistry (IHC)

Discover our top product MGP Primary Antibody

抗原表位
10

8

5

4

2

2

1

1

1
AA 20-96

原理

Anti-MGP Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-MGP Antibody Picoband® (ABIN4886666). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human MGP recombinant protein (Position: Y20-F96). Human MGP shares 84.4% and 80.5% amino acid (aa) sequence identity with mouse and rat MGP, respectively.

亚型

IgG
anti-Matrix Gla Protein (MGP) (AA 20-103) antibody
MGP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) antibody
MGP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 20-96) antibody
MGP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) antibody
MGP 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 37-66) antibody
MGP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 1-103) antibody
MGP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 20-104) antibody
MGP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 20-103) antibody
MGP 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Matrix Gla Protein (MGP) (AA 37-66) antibody
MGP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB12536 unconjugated

anti-Matrix Gla Protein (MGP) (AA 1-103) antibody
MGP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Hur, D. J., Raymond, G. V., Kahler, S. G., Riegert-Johnson, D. L., Cohen, B. A., Boyadjiev, S. A. A novel MGP mutation in a consanguineous family: review of the clinical and molecular characteristics of Keutel syndrome. Am. J. Med. Genet. 135A: 36-40, 2005. 2. Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G (March 1997). "Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein". Nature 386 (6620): 78-81. 3. Yao Y, Jumabay M, Ly A, Radparvar M, Cubberly MR, Boström KI (2013). "A role for the endothelium in vascular calcification". Circ. Res. 113 (5): 495-504.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

MGP (Matrix Gla Protein (MGP))

别名

MGP

背景

Synonyms: Matrix Gla protein,MGP,Cell growth-inhibiting gene 36 protein,MGP,MGLAP,GIG36,
Tissue Specificity: Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. .
Background: Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.

分子量

12 kDa

基因ID

4256

UniProt

P08493

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