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- 抗原 See all MGP 抗体
- MGP (Matrix Gla Protein (MGP))
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抗原表位
- AA 20-96
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MGP antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-MGP Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-MGP Antibody Picoband® (ABIN4886666). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human MGP recombinant protein (Position: Y20-F96). Human MGP shares 84.4% and 80.5% amino acid (aa) sequence identity with mouse and rat MGP, respectively.
- 亚型
- IgG
- Top Product
- Discover our top product MGP Primary Antibody
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anti-Matrix Gla Protein (MGP) (AA 20-103) antibody
MGP 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) antibodyMGP 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 20-96) antibodyMGP 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) antibodyMGP 适用: 人, 大鼠, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 37-66) antibodyMGP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 1-103) antibodyMGP 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 20-104) antibodyMGP 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 20-103) antibodyMGP 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (AA 1-103) antibodyMGP 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Matrix Gla Protein (MGP) (Middle Region) antibodyMGP 适用: 人, 大鼠, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Hur, D. J., Raymond, G. V., Kahler, S. G., Riegert-Johnson, D. L., Cohen, B. A., Boyadjiev, S. A. A novel MGP mutation in a consanguineous family: review of the clinical and molecular characteristics of Keutel syndrome. Am. J. Med. Genet. 135A: 36-40, 2005. 2. Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G (March 1997). "Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein". Nature 386 (6620): 78-81. 3. Yao Y, Jumabay M, Ly A, Radparvar M, Cubberly MR, Boström KI (2013). "A role for the endothelium in vascular calcification". Circ. Res. 113 (5): 495-504. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- MGP (Matrix Gla Protein (MGP))
- 别名
- MGP (MGP 产品)
- 背景
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Synonyms: Matrix Gla protein,MGP,Cell growth-inhibiting gene 36 protein,MGP,MGLAP,GIG36,
Tissue Specificity: Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. .
Background: Matrix Gla protein (MGP) is an 84-residue vitamin K-dependent protein initially isolated from bovine bone. In addition, MGP is a 10-kD protein produced and secreted by vascular smooth muscle cells and chondrocytes and significantly accumulated in bone, cartilage, and dentin. It is also expressed at high levels in heart, kidney, and lung and is upregulated by vitamin D in bone cells. MGP has a high affinity binding to calcium ions, similar to other Gla-containing proteins. The protein acts as an inhibitor of vascular mineralization and plays a role in bone organization. And this gene is mapped to 12p12.3.
- 分子量
- 12 kDa
- 基因ID
- 4256
- UniProt
- P08493
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