MEF2A 抗体 (C-Term)
Quick Overview for MEF2A 抗体 (C-Term) (ABIN4886665)
抗原
See all MEF2A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 466-507, C-Term
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原理
- Anti-MEF2A Antibody Picoband®
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序列
- DGSDREDPRG DFHSPIVLGR PPNTEDRESP SVKRMRMDAW
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MEF2A Antibody Picoband® (ABIN4886665). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human MEF2A, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
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亚型
- IgG
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anti-Myocyte Enhancer Factor 2A (MEF2A) (pThr312) antibody
MEF2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (pSer408) antibodyMEF2A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (pThr319) antibodyMEF2A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 71-170) antibodyMEF2A 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 71-170) antibodyMEF2A 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F8 unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (C-Term) antibodyMEF2A 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 71-170) antibodyMEF2A 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1D11 unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (pThr312) antibodyMEF2A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 391-497) antibodyMEF2A 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2F9H2 unconjugated
anti-Myocyte Enhancer Factor 2A (MEF2A) (AA 453-479) antibodyMEF2A 适用: 人, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
1. Bhagavatula, M. R. K., Fan, C., Shen, G.-Q., Cassano, J., Plow, E. F., Topol, E. J., Wang, Q. Transcription factor MEF2A mutations in patients with coronary artery disease. Hum. Molec. Genet. 13: 3181-3188, 2004. 2. Flavell, S. W., Cowan, C. W., Kim, T.-K., Greer, P. L., Lin, Y., Paradis, S., Griffith, E. C., Hu, L. S., Chen, C., Greenberg, M. E. Activity-dependent regulation of MEF2 transcription factors suppresses excitatory synapse number. Science 311: 1008-1012, 2006. 3. Gonzalez, P., Garcia-Castro, M., Reguero, J. R., Batalla, A., Ordonez, A. G., Palop, R. L., Lozano, I., Montes, M., Alvarez, V., Coto, E. The pro279leu variant in the transcription factor MEF2A is associated with myocardial infarction. (Letter) J. Med. Genet. 43: 167-169, 2006. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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别名
- MEF2A
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背景
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Synonyms: Myocyte-specific enhancer factor 2A,Serum response factor-like protein 1,MEF2A,MEF2,
Tissue Specificity: Isoform MEF2 and isoform MEFA are expressed only in skeletal and cardiac muscle and in the brain. Isoform RSRFC4 and isoform RSRFC9 are expressed in all tissues examined. .
Background: Myocyte-specific enhancer factor 2A is a protein that in humans is encoded by the MEF2A gene. It is mapped to 15q26. The protein encoded by this gene is a DNA-binding transcription factor that activates many muscle-specific, growth factor-induced, and stress-induced genes. The encoded protein can act as a homodimer or as a heterodimer and is involved in several cellular processes, including muscle development, neuronal differentiation, cell growth control, and apoptosis. Defects in this gene could be a cause of autosomal dominant coronary artery disease 1 with myocardial infarction (ADCAD1). Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 56 kDa
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基因ID
- 4205
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UniProt
- Q02078
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途径
- Neurotrophin Signaling Pathway, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
抗原
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