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- 抗原 See all IL12RB1 抗体
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
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抗原表位
- AA 624-662, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IL12RB1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 原理
- Rabbit IgG polyclonal antibody for Interleukin-12 receptor subunit beta-1 (IL12RB1) detection. Tested with WB in Human.
- 序列
- DKGERTEPLE KTELPEGAPE LALDTELSLE DGDRCKAKM
- 交叉反应 （详细）
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Interleukin-12 receptor subunit beta-1 (IL12RB1) detection. Tested with WB in Human.
Gene Name: interleukin 12 receptor subunit beta 1
Protein Name: Interleukin-12 receptor subunit beta-1 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human IL12RB1 (624-662aa DKGERTEPLEKTELPEGAPELALDTELSLEDGDRCKAKM).
- 亚型
- IgG
- Top Product
- Discover our top product IL12RB1 Primary Antibody
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anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 420-470) antibody
IL12RB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (Internal Region) antibodyIL12RB1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 37-234) antibodyIL12RB1 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibodyIL12RB1 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 197-348) antibodyIL12RB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 119-280) antibodyIL12RB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibodyIL12RB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))
- 别名
- IL12RB1 (IL12RB1 产品)
- 别名
- Il12rb antibody, IL12RB1 antibody, IL-12R antibody, CD212 antibody, IL-12R-BETA1 antibody, IL12RB antibody, IL-12R[b] antibody, interleukin 12 receptor subunit beta 1 antibody, interleukin 12 receptor, beta 1 antibody, Il12rb1 antibody, IL12RB1 antibody
- 背景
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IL12RB1, mapped to 19p13.11, is also known as CD212. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. And this protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.
Synonyms: CD212 | IL-12R-beta-1 | IL-12RB1 | IL12RB | Il12rb1 | IMD3 | IMD30 | P42701 - 基因ID
- 3594
- UniProt
- P42701
- 途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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