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IL12RB1 抗体 (C-Term)

This anti-IL12RB1 antibody is a 兔多克隆 antibody detecting IL12RB1 in WB. Suitable for 人.

Western blot analysis of IL12RB1 expression in HEPG2 whole cell lysates ( Lane 1). (IL12RB1 抗体 (C-Term))

1 image

产品编号 ABIN4886631

发货至: 中国

Quick Overview for IL12RB1 抗体 (C-Term) (ABIN4886631)

抗原

See all IL12RB1 抗体

IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

适用

人

宿主

兔

克隆类型

多克隆

标记

34
7
5
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
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1
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1

This IL12RB1 antibody is un-conjugated

应用范围

52
16
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11
8
3
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2
1
1

Western Blotting (WB)

Discover our top product IL12RB1 Primary Antibody

抗原表位
16

7

5

4

3

3

2

2

1

1

1

1

1

1

1

1

1
AA 624-662, C-Term

原理

Anti-IL12RB1 Antibody Picoband®

序列

DKGERTEPLE KTELPEGAPE LALDTELSLE DGDRCKAKM

交叉反应（详细）

No cross-reactivity with other proteins.

产品特性

Anti-IL12RB1 Antibody Picoband® (ABIN4886631). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the C-terminus of human IL12RB1.

亚型

IgG
anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 420-470) antibody
IL12RB1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibody
IL12RB1 适用: 人, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibody
IL12RB1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 37-234) antibody
IL12RB1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) antibody
IL12RB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 197-348) antibody
IL12RB1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 119-280) antibody
IL12RB1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (Internal Region) antibody
Verified IL12RB1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 1-381) antibody
IL12RB1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Interleukin 12 Receptor beta 1 (IL12RB1) (AA 25-305) antibody
IL12RB1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: IL12RB1 interleukin 12 receptor, beta 1". 2. Altare F, Ensser A, Breiman A, et al. (2001). "Interleukin-12 receptor beta1 deficiency in a patient with abdominal tuberculosis". J. Infect. Dis. 184 (2): 231-6. 3. Parham C, Chirica M, Timans J, et al. (2002). "A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R". J. Immunol. 168 (11): 5699-708.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

IL12RB1 (Interleukin 12 Receptor beta 1 (IL12RB1))

别名

IL12RB1

背景

Synonyms: Interleukin-12 receptor subunit beta-1,IL-12 receptor subunit beta-1,IL-12R subunit beta-1,IL-12R-beta-1,IL-12RB1,IL-12 receptor beta component,CD212,IL12RB1,IL12R, IL12RB,
Background: IL12RB1, mapped to 19p13.11, is also known as CD212. The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. And this protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. Mutations in this gene impair the development of interleukin-17-producing T lymphocytes and result in increased susceptibility to mycobacterial and Salmonella infections. Alternative splicing results in multiple transcript variants.

分子量

70 kDa

基因ID

3594

UniProt

P42701

途径

JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation

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