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HNRNPL 抗体 (C-Term)

This anti-HNRNPL antibody is a 兔 多克隆 antibody detecting HNRNPL in WB, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886624
发货至: 中国

Quick Overview for HNRNPL 抗体 (C-Term) (ABIN4886624)

抗原

See all HNRNPL 抗体
HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HNRNPL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    AA 546-571, C-Term

    原理

    Anti-HnRNP L/HNRNPL Antibody Picoband®

    序列

    LLEWESKSDA LETLGFLNHY QMKNPN

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-HnRNP L/HNRNPL Antibody Picoband® (ABIN4886624). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human HnRNP L, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    1. "Entrez Gene: HNRPL heterogeneous nuclear ribonucleoprotein L". 2. Hahm B, Cho OH, Kim JE, Kim YK, Kim JH, Oh YL, Jang SK (April 1998). "Polypyrimidine tract-binding protein interacts with HnRNP L". FEBS Lett. 425 (3): 401-6. 3. Pinol-Roma S, Swanson MS, Gall JG, Dreyfuss G (January 1990). "A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts". J Cell Biol. 109 (6 Pt 1): 2575-87.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    HNRNPL (Heterogeneous Nuclear Ribonucleoprotein L (HNRNPL))

    别名

    HNRNPL

    背景

    Synonyms: Heterogeneous nuclear ribonucleoprotein L,hnRNP L,HNRNPL,HNRPL,P/OKcl.14,

    Tissue Specificity: Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.

    Background: Heterogeneous nuclear ribonucleoprotein L is a protein that in humans is encoded by the HNRNPL gene. Heterogeneous nuclear RNAs (hnRNAs) which include mRNA precursors and mature mRNAs are associated with specific proteins to form heterogenous ribonucleoprotein (hnRNP) complexes. HNRNPL is among the proteins that are stably associated with hnRNP complexes and along with other hnRNP proteins is likely to play a major role in the formation, packaging, processing, and function of mRNA. It is present in the nucleoplasm as part of the HNRP complex. HNRP proteins have also been identified outside of the nucleoplasm. Exchange of hnRNP for mRNA-binding proteins accompanies transport of mRNA from the nucleus to the cytoplasm. Since HNRP proteins have been shown to shuttle between the nucleus and the cytoplasm, it is possible that they also have cytoplasmic functions. Two transcript variants encoding different isoforms have been found for this gene.

    分子量

    64 kDa

    基因ID

    3191

    UniProt

    P14866
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