Hexokinase 2 抗体 (Middle Region)
Quick Overview for Hexokinase 2 抗体 (Middle Region) (ABIN4886617)
抗原
See all Hexokinase 2 (HK2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 460-497, Middle Region
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原理
- Anti-Hexokinase II/HK2 Antibody Picoband®
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序列
- AYRLADQHRA RQKTLEHLQL SHDQLLEVKR RMKVEME
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Hexokinase II/HK2 Antibody Picoband® (ABIN4886617). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Hexokinase II, different from the related mouse and rat sequences by four amino acids.
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亚型
- IgG
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anti-Hexokinase 2 (HK2) (AA 1-120) antibody
HK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Hexokinase 2 (HK2) (AA 818-917) antibodyHK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (C-Term) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) (AA 469-669) antibodyHK2 适用: 人 WB, IHC, IP, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 453-483) antibodyHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5333 unconjugated
anti-Hexokinase 2 (HK2) (AA 334-526) antibodyHK2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. "Entrez Gene: HK2 hexokinase 2". 2. Printz RL, Osawa H, Ardehali H, Koch S, Granner DK (Feb 1997). "Hexokinase II gene: structure, regulation and promoter organization". Biochemical Society Transactions. 25 (1): 107-12. 3. Peng Q, Zhou J, Zhou Q, Pan F, Zhong D, Liang H (2009). "Silencing hexokinase II gene sensitizes human colon cancer cells to 5-fluorouracil". Hepato-Gastroenterology. 56 (90): 355-60. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Hexokinase 2 (HK2)
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别名
- HK2
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背景
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Synonyms: Hexokinase-2,2.7.1.1,Hexokinase type II,HK II,Muscle form hexokinase,HK2,
Tissue Specificity: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle.
Background: Hexokinase 2, also known as HK2, is an enzyme which in humans is encoded by the HK2 gene on chromosome 2. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
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分子量
- 102 kDa
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基因ID
- 3099
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UniProt
- P52789
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途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
抗原
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