GNB1 抗体 (N-Term)
Quick Overview for GNB1 抗体 (N-Term) (ABIN4886607)
抗原
See all GNB1 抗体适用
宿主
克隆类型
标记
应用范围
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                                            抗原表位
- AA 2-42, N-Term
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                                            原理
- Anti-GNB1 Antibody Picoband®
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                                            序列
- SELDQLRQEA EQLKNQIRDA RKACADATLS QITNNIDPVG R
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                                            交叉反应 (详细)
- No cross-reactivity with other proteins
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                                            产品特性
- Anti-GNB1 Antibody Picoband® (ABIN4886607). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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                                            纯化方法
- Immunogen affinity purified.
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                                            免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human GNB1, identical to the related mouse and rat sequences.
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                                            亚型
- IgG
 
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                                            应用备注
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                        Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
 Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
 Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
 Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
 Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
 1. Codina J, Stengel D, Woo SL, Birnbaumer L (1986). "Beta-subunits of the human liver Gs/Gi signal-transducing proteins and those of bovine retinal rod cell transducin are identical". FEBS Lett. 207 (2): 187-92. 2. Yan K, Kalyanaraman V, Gautam N (March 1996). "Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families". J. Biol. Chem. 271 (12): 7141-6.
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                                            说明
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                        Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P). 
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                                            限制
- 仅限研究用
 
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                                            状态
- Lyophilized
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                                            溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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                                            浓度
- 500 μg/mL
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                                            缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            注意事项
- Avoid repeated freezing and thawing.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
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                        Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. 
 It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
 
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    - GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))
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                                            别名
- GNB1
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                                            背景
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                        Synonyms: Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-1,Transducin beta chain 1,GNB1, Tissue Specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine. Background: Guanine nucleotide-binding protein G (I)/G (S)/G (T) subunit beta-1 is a protein that in humans is encoded by the GNB1 gene. Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. This gene uses alternative polyadenylation signals. 
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                                            分子量
- 37 kDa
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                                            基因ID
- 2782
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                                            UniProt
- P62873
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                                            途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
 抗原
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