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GLRX3 抗体 (AA 89-177)

This anti-GLRX3 antibody is a 兔 多克隆 antibody detecting GLRX3 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886606
发货至: 中国

Quick Overview for GLRX3 抗体 (AA 89-177) (ABIN4886606)

抗原

See all GLRX3 抗体
GLRX3 (Glutaredoxin 3 (GLRX3))

适用

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人, 小鼠, 大鼠

宿主

  • 47
  • 7
  • 3

克隆类型

  • 52
  • 5
多克隆

标记

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This GLRX3 antibody is un-conjugated

应用范围

  • 51
  • 24
  • 19
  • 15
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  • 8
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  • 2
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Western Blotting (WB)
  • 抗原表位

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    • 1
    AA 89-177

    原理

    Anti-TXNL2/GLRX3 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-TXNL2/GLRX3 Antibody Picoband® (ABIN4886606). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human TXNL2 recombinant protein (Position: L89-S177). Human TXNL2 shares 93.3% and 94.4% amino acid (aa) sequence identity with mouse and rat TXNL2, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
    1. Stanchi F, Bertocco E, Toppo S, Dioguardi R, Simionati B, Cannata N, Zimbello R, Lanfranchi G, Valle G (Jan 2001). "Characterization of 16 novel human genes showing high similarity to yeast sequences". Yeast 18 (1): 69-80. 2. Witte S, Villalba M, Bi K, Liu Y, Isakov N, Altman A (Feb 2000). "Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain". J Biol Chem 275 (3): 1902-9.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GLRX3 (Glutaredoxin 3 (GLRX3))

    别名

    GLRX3

    背景

    Synonyms: Glutaredoxin-3,PKC-interacting cousin of thioredoxin,PICOT,PKC-theta-interacting protein,PKCq-interacting protein,Thioredoxin-like protein 2,GLRX3,PICOT, TXNL2,HUSSY-22,

    Tissue Specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.

    Background: Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.

    分子量

    37 kDa

    基因ID

    10539

    UniProt

    O76003

    途径

    Cell RedoxHomeostasis
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