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GLA 抗体 (C-Term)

This anti-GLA antibody is a 兔 多克隆 antibody detecting GLA in WB. Suitable for 小鼠 和 大鼠.
产品编号 ABIN4886604
发货至: 中国

Quick Overview for GLA 抗体 (C-Term) (ABIN4886604)

抗原

See all GLA 抗体
GLA (Galactosidase, alpha (GLA))

适用

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小鼠, 大鼠

宿主

  • 102
  • 18
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克隆类型

  • 94
  • 28
多克隆

标记

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This GLA antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 218-275, C-Term

    原理

    Anti-Galactosidase alpha/Gla Antibody Picoband®

    序列

    DIQYYCNHWR NFDDVYDSWE SIKNILSWTV VYQKEIVEVA

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Galactosidase alpha/Gla Antibody Picoband® (ABIN4886604). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Gla, different from the related human sequence by fifteen amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    1. "Entrez Gene: GLA galactosidase, alpha". 2. Calhoun DH, Bishop DF, Bernstein HS, Quinn M, Hantzopoulos P, Desnick RJ (1985). "Fabry disease: isolation of a cDNA clone encoding human alpha-galactosidase A". Proceedings of the National Academy of Sciences of the United States of America. 82 (21): 7364-8. 3. Keating GM (October 2012). "Agalsidase alfa: a review of its use in the management of Fabry disease". BioDrugs. 26 (5): 335-54.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    GLA (Galactosidase, alpha (GLA))

    别名

    Gla

    背景

    Synonyms: Alpha-galactosidase A,3.2.1.22 ,Alpha-D-galactosidase A,Alpha-D-galactoside galactohydrolase,Melibiase,Gla,Ags,

    Background: Alpha-galactosidase is a glycoside hydrolase enzyme that encoded by the GLA gene. This gene is a homodimeric glycoprotein that hydrolyses the terminal alpha-galactosyl moieties from glycolipids and glycoproteins. This enzyme predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose. A variety of mutations in this gene affect the synthesis, processing, and stability of this enzyme, which causes Fabry disease, a rare lysosomal storage disorder that results from a failure to catabolize alpha-D-galactosyl glycolipid moieties.

    分子量

    49 kDa

    基因ID

    11605

    UniProt

    P51569

    途径

    SARS-CoV-2 Protein Interactome
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