E2F4 抗体 (N-Term)
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北京 101111
Quick Overview for E2F4 抗体 (N-Term) (ABIN4886566)
抗原
See all E2F4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Anti-E2F4 Antibody
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序列
- ELQQREQELD QHKVWVQQSI RNVTEDVQNS CLAYVTHED
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- identical to the related mouse,rat sequences.
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产品特性
- Anti-E2F4 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human E2F4, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibody
E2F4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 211-301) antibodyE2F4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5B7 unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyKD Validated E2F4 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB5375 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (C-Term) antibodyE2F4 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 马, 兔, 犬, Pig, 猴, 豚鼠, 斑马鱼, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 1-413) antibodyE2F4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 160-299) antibodyE2F4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) antibodyE2F4 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (acLys96) antibodyE2F4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 4, P107/p130-Binding (E2F4) (AA 363-413) antibodyE2F4 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- E2F4 (E2F Transcription Factor 4, P107/p130-Binding (E2F4))
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别名
- E2F4
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背景
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Background: Transcription factor E2F4 is a protein that in humans is encoded by the E2F4 gene. The protein encoded by this gene is a member of the E2F family of transcription factors. This gene is mapped to 16q22.1. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. Additionally, it plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer.
Gene Full Name: E2F transcription factor 4
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分子量
- 44 kDa, 60 kDa
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基因ID
- 1874
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UniProt
- Q16254
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Regulation of Cell Size
抗原
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