DDAH1 抗体 (C-Term)
Quick Overview for DDAH1 抗体 (C-Term) (ABIN4886560)
抗原
See all DDAH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 195-226, C-Term
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原理
- Anti-DDAH1 Antibody Picoband®
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序列
- QKALKIMQQM SDHRYDKLTV PDDIAANCIY LN
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-DDAH1 Antibody Picoband® (ABIN4886560). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human DDAH1, different from the related mouse and rat sequences by one amino acid.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. Dayoub, H., Achan, V., Adimoolam, S., Jacobi, J., Stuehlinger, M. C., Wang, B., Tsao, P. S., Kimoto, M., Vallance, P., Patterson, A. J., Cooke, J. P. Dimethylarginine dimethylaminohydrolase regulates nitric oxide synthesis: genetic and physiological evidence.Circulation 108: 3042-3047, 2003. 2. Millatt, L. J., Whitley, G. StJ., Li, D., Leiper, J. M., Siragy, H. M., Carey, R. M., Johns, R. A. Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension. Circulation 108: 1493-1498, 2003. 3. Tran, C. T. L., Fox, M. F., Vallance, P., Leiper, J. M. Chromosomal localization, gene structure, and expression pattern of DDAH1: comparison with DDAH2 and implications for evolutionary origins. Genomics 68: 101-105, 2000. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- DDAH1 (Dimethylarginine Dimethylaminohydrolase 1 (DDAH1))
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别名
- DDAH1
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背景
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Synonyms: N (G),N (G)-dimethylarginine dimethylaminohydrolase 1,DDAH-1,Dimethylarginine dimethylaminohydrolase 1,3.5.3.18,DDAHI,Dimethylargininase-1,DDAH1,DDAH,
Tissue Specificity: Detected in brain, liver, kidney and pancreas, and at low levels in skeletal muscle. .
Background: DDAH1 is knowns as dimethylarginine dimethylaminohydrolase 1 which is mapped to chromosome 1p22 by radiation hybrid and FISH analysis. This gene belongs to the dimethylarginine dimethylaminohydrolase (DDAH) gene family. DDAH1 plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. It widely expressed, especially in liver and kidney.
Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.
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分子量
- 31 kDa, 37 kDa
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基因ID
- 23576
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UniProt
- O94760
抗原
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