CRYAA 抗体 (AA 1-173)
Quick Overview for CRYAA 抗体 (AA 1-173) (ABIN4886549)
抗原
See all CRYAA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-173
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原理
- Anti-Alpha A Crystallin/CRYAA Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Alpha A Crystallin/CRYAA Antibody Picoband® (ABIN4886549). Tested in Flow Cytometry, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Alpha A Crystallin recombinant protein (Position: M1-S173). Human Alpha A Crystallin shares 94.8% amino acid (aa) sequence identity with both mouse and rat Alpha A Crystallin.
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亚型
- IgG
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anti-Crystallin, alpha A (CRYAA) antibody
CRYAA 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 1-173) antibodyCRYAA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Crystallin, alpha A (CRYAA) antibodyCRYAA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Crystallin, alpha A (CRYAA) (AA 77-106) antibodyCRYAA 适用: 人 WB 宿主: 兔 Polyclonal RB28544 unconjugated
anti-Crystallin, alpha A (CRYAA) antibody (Atto 594)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Atto 594
anti-Crystallin, alpha A (CRYAA) antibody (Atto 488)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Atto 488
anti-Crystallin, alpha A (CRYAA) antibody (Atto 390)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 Atto 390
anti-Crystallin, alpha A (CRYAA) antibodyCRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 unconjugated
anti-Crystallin, alpha A (CRYAA) antibody (HRP)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 HRP
anti-Crystallin, alpha A (CRYAA) antibody (FITC)CRYAA 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 1H3-B8 FITC
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
Immunocytochemistry, 0.5-1 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
1. "Entrez Gene: CRYAA crystallin, alpha A". 2. Derham BK, Harding JJ (1999). "Alpha-crystallin as a molecular chaperone.". Progress in retinal and eye research 18 (4): 463-509. 3. Jaworski CJ, Piatigorsky J (1989). "A pseudo-exon in the functional human alpha A-crystallin gene.". Nature337 (6209): 752-4. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CRYAA (Crystallin, alpha A (CRYAA))
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别名
- CRYAA
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背景
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Synonyms: Alpha-crystallin A chain,Heat shock protein beta-4,HspB4,Alpha-crystallin A (1-172),Alpha-crystallin A (1-168),Alpha-crystallin A (1-162),CRYAA,CRYA1, HSPB4,
Tissue Specificity: Expressed in eye lens. .
Background: Alpha-crystallin A chain is a protein that in humans is encoded by the CRYAA gene. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone, instead they hold them in large soluble aggregates. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed, alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).
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分子量
- 20 kDa
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基因ID
- 1409
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UniProt
- P02489
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途径
- M Phase
抗原
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