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CPB2 抗体 (AA 165-387)

This anti-CPB2 antibody is a 兔 多克隆 antibody detecting CPB2 in WB. Suitable for 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN4886546
发货至: 中国

Quick Overview for CPB2 抗体 (AA 165-387) (ABIN4886546)

抗原

See all CPB2 抗体
CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This CPB2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 165-387

    原理

    Anti-Carboxypeptidase B2/CPB2 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Carboxypeptidase B2/CPB2 Antibody Picoband® (ABIN4886546). Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1% and 96.9% amino acid (aa) sequence identity with human and rat CPB2, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Mouse
    1. Boffa MB, Reid TS, Joo E, Nesheim ME, Koschinsky ML (May 1999). "Characterization of the gene encoding human TAFI (thrombin-activable fibrinolysis inhibitor, plasma procarboxypeptidase B)". Biochemistry 38 (20): 6547-58. 2. Eaton DL, Malloy BE, Tsai SP, Henzel W, Drayna D (Dec 1991). "Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma". J Biol Chem 266 (32): 21833-8. 3. Tsai SP, Drayna D (Dec 1992). "The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13". Genomics14 (2): 549-50.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Qin, Zeng, Tian, Deng, Ren, Zheng, Li, Li, Liao, Chen: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).

  • 抗原

    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

    别名

    Cpb2

    背景

    Synonyms: Carboxypeptidase B2,3.4.17.20,Carboxypeptidase R,CPR,Carboxypeptidase U,CPU,Thrombin-activable fibrinolysis inhibitor,TAFI,Cpb2,Tafi,

    Tissue Specificity: Plasma, synthesized in the liver. .

    Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

    分子量

    48 kDa

    基因ID

    56373

    途径

    Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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