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CPB2 抗体 (AA 166-388)

Name: CPB2 抗体 (AA 166-388)
SKU: ABIN4886545
Availability: OutOfStock

CPB2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of CPB2 expression in human placenta extract ( Lane 1) and HEPG2 whole cell lysates ( Lane 2). (CPB2 抗体 (AA 166-388))

CPB2 was detected in paraffin-embedded sections of human lung cancer tissues using rabbit anti- CPB2 Antigen Affinity purified polyclonal antibody (Catalog # ) at 1 µg/mL. (CPB2 抗体 (AA 166-388))

IHC

2 images

(1 reference)

产品编号 ABIN4886545

发货至: 中国

Datasheet as PDF

抗原 See all CPB2 抗体

CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
抗原表位
15

7

4

4

4

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 166-388
适用
55

30

14

2

1

1

1

1
人
宿主
65

9

4
兔
Compatible Secondaries
克隆类型
70

8
多克隆
标记
38

9

8

5

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This CPB2 antibody is un-conjugated
应用范围
46

24

20

17

17

13

13

4

4

4

3

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

原理

Anti-Carboxypeptidase B2/CPB2 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Carboxypeptidase B2/CPB2 Antibody Picoband® (ABIN4886545). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1% and 85.7% amino acid (aa) sequence identity with mouse and rat CPB2, respectively.

亚型

IgG

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CPB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibody
CPB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibody
CPB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 324-373) antibody
CPB2 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 165-387) antibody
CPB2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated

anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 309-374) antibody
CPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA(Cap) , 1-5 μg/mL, Human, -
1. Boffa MB, Reid TS, Joo E, Nesheim ME, Koschinsky ML (May 1999). "Characterization of the gene encoding human TAFI (thrombin-activable fibrinolysis inhibitor, plasma procarboxypeptidase B)". Biochemistry 38 (20): 6547-58. 2. Eaton DL, Malloy BE, Tsai SP, Henzel W, Drayna D (Dec 1991). "Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma". J Biol Chem 266 (32): 21833-8. 3. Tsai SP, Drayna D (Dec 1992). "The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13". Genomics14 (2): 549-50.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Qin, Zeng, Tian, Deng, Ren, Zheng, Li, Li, Liao, Chen: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).
抗原

CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))

别名

CPB2 (CPB2 产品)

背景

Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,
Tissue Specificity: Plasma, synthesized in the liver.
Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

分子量

48 kDa, 60 kDa

基因ID

1361

途径

Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis