CPB2 抗体 (AA 166-388)
(1 reference)Quick Overview for CPB2 抗体 (AA 166-388) (ABIN4886545)
抗原
See all CPB2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 166-388
-
原理
- Anti-Carboxypeptidase B2/CPB2 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Carboxypeptidase B2/CPB2 Antibody Picoband® (ABIN4886545). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human CPB2 recombinant protein (Position: K166-D388). Human CPB2 shares 86.1% and 85.7% amino acid (aa) sequence identity with mouse and rat CPB2, respectively.
-
亚型
- IgG
-
-
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 113-422) antibody
CPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 138-386) antibodyCPB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 187-327) antibodyCPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 225-372) antibodyCPB2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 164-417) antibodyCPB2 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 1-423) antibodyCPB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 324-373) antibodyCPB2 适用: 人, 犬, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 165-387) antibodyCPB2 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Carboxypeptidase B2 (Plasma) (CPB2) (AA 309-374) antibodyCPB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA(Cap) , 1-5 μg/mL, Human, -
1. Boffa MB, Reid TS, Joo E, Nesheim ME, Koschinsky ML (May 1999). "Characterization of the gene encoding human TAFI (thrombin-activable fibrinolysis inhibitor, plasma procarboxypeptidase B)". Biochemistry 38 (20): 6547-58. 2. Eaton DL, Malloy BE, Tsai SP, Henzel W, Drayna D (Dec 1991). "Isolation, molecular cloning, and partial characterization of a novel carboxypeptidase B from human plasma". J Biol Chem 266 (32): 21833-8. 3. Tsai SP, Drayna D (Dec 1992). "The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13". Genomics14 (2): 549-50. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
-
: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).
-
: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." in: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).
-
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
-
别名
- CPB2
-
背景
-
Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,
Tissue Specificity: Plasma, synthesized in the liver.
Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
-
分子量
- 48 kDa, 60 kDa
-
基因ID
- 1361
-
途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
抗原
-
