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CACYBP 抗体 (N-Term)

This anti-CACYBP antibody is a 兔 多克隆 antibody detecting CACYBP in WB, IF, IHC, ICC, IP 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886495
发货至: 中国

Quick Overview for CACYBP 抗体 (N-Term) (ABIN4886495)

抗原

See all CACYBP 抗体
CACYBP (Calcyclin Binding Protein (CACYBP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CACYBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 抗原表位

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    AA 7-47, N-Term

    原理

    Anti-SIAH Interacting Protein/CACYBP Antibody Picoband®

    序列

    QKDLEEVKVL LEKATRKRVR DALTAEKSKI ETEIKNKMQQ K

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-SIAH Interacting Protein/CACYBP Antibody (ABIN4886495). Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human CACYBP, different from the related mouse sequence by five amino acids, and from the related rat sequence by six amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence,2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    Immunoprecipitation, 0.5-2 μg/mL, Human
    1. Matsuzawa, S., Reed, J. C. Siah-1, SIP, and Ebi collaborate in a novel pathway for beta-catenin degradation linked to p53 responses.Molec. Cell 7: 915-926, 2001. 2. Sun S, Ning X, Liu J, et al. (2007). "Overexpressed CacyBP/SIP leads to the suppression of growth in renal cell carcinoma.". Biochem. Biophys. Res. Commun. 356 (4): 864-71.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    CACYBP (Calcyclin Binding Protein (CACYBP))

    别名

    CACYBP

    背景

    Synonyms: Calcyclin-binding protein,CacyBP,hCacyBP,S100A6-binding protein,Siah-interacting protein,CACYBP,S100A6BP, SIP,PNAS-107,

    Tissue Specificity: Widely expressed.

    Background: Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene. And this gene is mapped to 1q24-q25. The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. In addition, it probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

    分子量

    26 kDa

    基因ID

    27101

    途径

    Response to Growth Hormone Stimulus
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