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C1QBP 抗体 (AA 190-282)

This anti-C1QBP antibody is a 兔 多克隆 antibody detecting C1QBP in WB, IHC, ICC, IF, FACS 和 IHC (fro). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886491
发货至: 中国

Quick Overview for C1QBP 抗体 (AA 190-282) (ABIN4886491)

抗原

See all C1QBP 抗体
C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

适用

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人, 小鼠, 大鼠

宿主

  • 100
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  • 1

克隆类型

  • 89
  • 40
多克隆

标记

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This C1QBP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 190-282

    原理

    Anti-GC1q R/C1QBP Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-GC1q R/C1QBP Antibody Picoband® (ABIN4886491). Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human GC1q R recombinant protein (Position: E190-Q282). Human GC1q R shares 92.5% and 93.5% amino acid (aa) sequence identity with mouse and rat GC1q R, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: C1QBP complement component 1, q subcomponent binding protein". 2. Deb TB, Datta K (March 1996). "Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2". J Biol Chem 271 (4): 2206-12. 3. Ghebrehiwet B, Lim BL, Peerschke EI, Willis AC, Reid KB (June 1994). "Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular "heads" of C1q". J Exp Med 179(6): 1809-21.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    C1QBP (Complement Component 1, Q Subcomponent Binding Protein (C1QBP))

    别名

    C1QBP

    背景

    Synonyms: Complement component 1 Q subcomponent-binding protein, mitochondrial,ASF/SF2-associated protein p32,Glycoprotein gC1qBP,C1qBP,Hyaluronan-binding protein 1,Mitochondrial matrix protein p32,gC1q-R protein,p33,C1QBP,GC1QBP, HABP1, SF2P32,

    Tissue Specificity: Expressed on cell surface of peripheral blood cells (at protein level), Surface expression is reported for macrophages and monocyte-derived dendritic cells. .

    Background: Complement component 1 Q subcomponent-binding protein, mitochondrial is a protein that in humans is encoded by the C1QBP gene. This gene is mapped to 17p13.3 in a region conserved with mouse chromosome 11. The human complement subcomponent C1q associates with C1r and C1s in order to yield the first component of the serum complement system. The protein encoded by this gene is known to bind to the globular heads of C1q molecules and inhibit C1 activation. This protein has also been identified as the p32 subunit of pre-mRNA splicing factor SF2, as well as a hyaluronic acid-binding protein.

    分子量

    35 kDa

    基因ID

    708

    UniProt

    Q07021

    途径

    Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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