ANG 抗体 (AA 25-147)
Quick Overview for ANG 抗体 (AA 25-147) (ABIN4886457)
抗原
See all ANG 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-147
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原理
- Anti-Angiogenin/ANG Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Angiogenin/ANG Antibody Picoband® (ABIN4886457). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Angiogenin/ANG recombinant protein (Position: Q25-P147). Human Angiogenin/ANG shares 77.5% amino acid (aa) sequence identity with mouse Angiogenin/ANG.
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亚型
- IgG
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anti-Angiogenin (ANG) (AA 25-147) antibody
ANG 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) (AA 25-142) antibodyANG 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) antibodyANG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) (AA 25-147) antibodyANG 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Angiogenin (ANG) (AA 25-147) antibodyANG 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C9 unconjugated
anti-Angiogenin (ANG) (AA 25-147) antibodyANG 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) (N-Term) antibodyANG 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) (AA 26-147) antibodyANG 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiogenin (ANG) (AA 24-148) antibodyANG 适用: Cow WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D4 unconjugated
anti-Angiogenin (ANG) (AA 25-145) antibodyANG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
ELISA(Cap) , 1-5 μg/mL, Human, -
1. Gao X, Xu Z (2008). "Mechanisms of action of angiogenin". Acta Biochimica et Biophysica Sinica. 40 (7): 619-624. 2. Tello-Montoliu A, Patel J.V., Lip G.Y.H. (2006). "Angiogenin: a review of the pathophysiology and potential clinical applications". Journal of Thrombosis and Haemostasis. 4 (9): 1864-74. 3. Tsuji T, Sun Y, Kishimoto K, Olson K, Luo S, Hirukawa S, Hu G (2005). "Angiogenin is translocated to the nucleus of HeLa cells and is involved in ribosomal RNA transcription and cell proliferation". Cancer Research (65): 1352. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ANG (Angiogenin (ANG))
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别名
- ANG
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背景
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Synonyms: Angiogenin,3.1.27.-,Ribonuclease 5,RNase 5,ANG,RNASE5,
Tissue Specificity: Expressed predominantly in the liver. Also detected in endothelial cells and spinal cord neurons. .
Background: Angiogenin (Ang), also known as ribonuclease 5, is a small 123 amino acid protein that in humans is encoded by the ANG gene. The protein encoded by this gene is an exceedingly potent mediator of new blood vessel formation. It hydrolyzes cellular tRNAs resulting in decreased protein synthesis and is similar to pancreatic ribonuclease. In addition, the mature peptide has antimicrobial activity against some bacteria and fungi, including S. pneumoniae and C. albicans. Alternative splicing results in two transcript variants encoding the same protein. This gene and the gene that encodes ribonuclease, RNase A family, 4 share promoters and 5' exons. Each gene splices to a unique downstream exon that contains its complete coding region.
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分子量
- 17 kDa
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基因ID
- 283
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UniProt
- P03950
抗原
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