AFG3L2 抗体 (AA 168-250)
Quick Overview for AFG3L2 抗体 (AA 168-250) (ABIN4886437)
抗原
See all AFG3L2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 168-250
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原理
- Anti-AFG3L2 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-AFG3L2 Antibody Picoband® (ABIN4886437). Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human AFG3L2 recombinant protein (Position: R168-D250). Human AFG3L2 shares 100% amino acid (aa) sequence identity with mouse AFG3L2.
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亚型
- IgG
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anti-AFG3-Like Protein 2 (AFG3L2) (AA 538-797) antibody
AFG3L2 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 550-759) antibodyAFG3L2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (C-Term) antibodyAFG3L2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 1-797) antibodyAFG3L2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) antibody (Biotin)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-AFG3-Like Protein 2 (AFG3L2) antibody (HRP)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP
anti-AFG3-Like Protein 2 (AFG3L2) antibody (FITC)AFG3L2 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-AFG3-Like Protein 2 (AFG3L2) (AA 324-373) antibodyAFG3L2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 1-250) antibodyAFG3L2 适用: 人 WB 宿主: 小鼠 Monoclonal 2D3 unconjugated
anti-AFG3-Like Protein 2 (AFG3L2) (AA 52-80), (N-Term) antibodyAFG3L2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33011 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: AFG3 ATPase family gene 3-like 2 (S. cerevisiae)". 2. Koppen, M., Metodiev, M. D., Casari, G., Rugarli, E. I., Langer, T. Variable and tissue-specific subunit composition of mitochondrial m-AAA protease complexes linked to hereditary spastic paraplegia. Molec. Cell. Biol. 27: 758-767, 2007. 3. Pierson TM, Adams D, Bonn F, Martinelli P, Cherukuri PF, Teer JK, Hansen NF, Cruz P, Mullikin For The Nisc Comparative Sequencing Program JC, Blakesley RW, Golas G, Kwan J, Sandler A, Fuentes Fajardo K, Markello T, Tifft C, Blackstone C, Rugarli EI, Langer T, Gahl WA, Toro C (October 2011). "Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases". PLoS Genet. 7 (10): e1002325. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- AFG3L2 (AFG3-Like Protein 2 (AFG3L2))
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别名
- AFG3L2
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背景
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Synonyms: AFG3-like protein 2,3.4.24.-,Paraplegin-like protein,AFG3L2,
Tissue Specificity: Ubiquitous. Highly expressed in the cerebellar Purkinje cells. .
Background: AFG3L2 is the catalytic subunit of the m-AAA protease, an ATP-dependent proteolytic complex of the mitochondrial inner membrane that degrades misfolded proteins and regulates ribosome assembly. In humans, it is encoded by the AFG3L2 gene. This gene encodes a protein localized in mitochondria and closely related to paraplegin. The paraplegin gene is responsible for an autosomal recessive form of hereditary spastic paraplegia. And this gene is a candidate gene for other hereditary spastic paraplegias or neurodegenerative disorders as well as spastic ataxia-neuropathy syndrome.
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分子量
- 89 kDa
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基因ID
- 10939
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UniProt
- Q9Y4W6
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途径
- Skeletal Muscle Fiber Development
抗原
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