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ADH5 抗体 (AA 212-374)

This 兔 多克隆 anti-ADH5 antibody specifically detects ADH5 in WB, IHC, IF 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN4886429
发货至: 中国
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Quick Overview for ADH5 抗体 (AA 212-374) (ABIN4886429)

抗原

See all ADH5 抗体
ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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  • 14
多克隆

标记

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This ADH5 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
    • 9
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    AA 212-374

    原理

    Anti-Alcohol dehydrogenase class-3 ADH5 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-Alcohol dehydrogenase class-3 ADH5 Antibody (ABIN4886429). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human ADH5 recombinant protein (Position: K212-I374). Human ADH5 shares 90.2% and 92% amino acid (aa) sequence identity with mouse and rat ADH5, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))

    别名

    ADH5

    背景

    Synonyms: Alcohol dehydrogenase class-3,1.1.1.1,Alcohol dehydrogenase 5,Alcohol dehydrogenase class chi chain,Alcohol dehydrogenase class-III,Glutathione-dependent formaldehyde dehydrogenase,FALDH,FDH,GSH-FDH,1.1.1.-,S- (hydroxymethyl)glutathione dehydrogenase,1.1.1.284,ADH5 ,ADHX, FDH,

    Tissue Specificity: Detected in cardiac myocytes.

    Background: Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

    分子量

    39 kDa

    基因ID

    128

    UniProt

    P11766
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