ADH5 抗体 (AA 212-374)
Quick Overview for ADH5 抗体 (AA 212-374) (ABIN4886429)
抗原
See all ADH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 212-374
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原理
- Anti-Alcohol dehydrogenase class-3 ADH5 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Alcohol dehydrogenase class-3 ADH5 Antibody (ABIN4886429). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human ADH5 recombinant protein (Position: K212-I374). Human ADH5 shares 90.2% and 92% amino acid (aa) sequence identity with mouse and rat ADH5, respectively.
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亚型
- IgG
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anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 1-374) antibody
ADH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 212-239) antibodyADH5 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22372 unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 14-130) antibodyADH5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 1-374) antibodyADH5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 1-374) antibodyADH5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 1-374) antibodyADH5 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 12F7 unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 82-165) antibodyADH5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (C-Term) antibodyADH5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) antibodyADH5 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (AA 2-374) antibodyADH5 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human1. Adinolfi A, Adinolfi M, Hopkinson DA (May 1984). "Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme". Ann Hum Genet 48 (Pt 1): 1-10. 2. Hur MW, Edenberg HJ (Dec 1992). "Cloning and characterization of the ADH5 gene encoding human alcohol dehydrogenase 5, formaldehyde dehydrogenase". Gene 121(2): 305-11. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
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别名
- ADH5
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背景
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Synonyms: Alcohol dehydrogenase class-3,1.1.1.1,Alcohol dehydrogenase 5,Alcohol dehydrogenase class chi chain,Alcohol dehydrogenase class-III,Glutathione-dependent formaldehyde dehydrogenase,FALDH,FDH,GSH-FDH,1.1.1.-,S- (hydroxymethyl)glutathione dehydrogenase,1.1.1.284,ADH5 ,ADHX, FDH,
Tissue Specificity: Detected in cardiac myocytes.
Background: Alcohol dehydrogenase class-3 is an enzyme that in humans is encoded by the ADH5 gene. This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
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分子量
- 39 kDa
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基因ID
- 128
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UniProt
- P11766
抗原
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