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ADH4 抗体 (AA 218-380)

This anti-ADH4 antibody is a 兔 多克隆 antibody detecting ADH4 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN4886428
发货至: 中国

Quick Overview for ADH4 抗体 (AA 218-380) (ABIN4886428)

抗原

See all ADH4 抗体
ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

适用

  • 32
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 27
  • 5

克隆类型

  • 29
  • 3
多克隆

标记

  • 20
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ADH4 antibody is un-conjugated

应用范围

  • 25
  • 15
  • 13
  • 9
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 218-380

    原理

    Anti-ADH4 Antibody Picoband®

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ADH4 Antibody Picoband® (ABIN4886428). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human ADH4 recombinant protein (Position: K218-F380). Human ADH4 shares 68.7% and 71.8% amino acid (aa) sequence identity with mouse and rat ADH4, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Li M, Edenberg HJ (1998). "Function of cis-acting elements in human alcohol dehydrogenase 4 (ADH4) promoter and role of C/EBP proteins in gene expression.". DNA Cell Biol. 17 (4): 387-97. 2. Luo X, Kranzler HR, Zuo L, et al. (2006). "ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies.".Pharmacogenet. Genomics 15(11): 755-68.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ADH4 (Alcohol Dehydrogenase 4 (Class II), pi Polypeptide (ADH4))

    别名

    ADH4

    背景

    Synonyms: Alcohol dehydrogenase 4,1.1.1.1,Alcohol dehydrogenase class II pi chain,ADH4,

    Tissue Specificity: Plasma. Expressed primarily in liver. .

    Background: Alcohol dehydrogenase 4 is an enzyme that in humans is encoded by the ADH4 gene. This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.

    分子量

    40 kDa

    基因ID

    127

    UniProt

    P08319

    途径

    Transition Metal Ion Homeostasis
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