电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

ADAR 抗体 (AA 128-346)

ADAR 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN4886426
发货至: 中国
  • 抗原 See all ADAR 抗体
    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
    抗原表位
    • 15
    • 15
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 128-346
    适用
    • 85
    • 29
    • 24
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 81
    • 5
    • 1
    克隆类型
    • 73
    • 14
    多克隆
    标记
    • 37
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ADAR antibody is un-conjugated
    应用范围
    • 57
    • 27
    • 27
    • 22
    • 20
    • 10
    • 9
    • 9
    • 7
    • 6
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    原理
    Anti-ADAR1 Antibody Picoband®
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-ADAR1 Antibody Picoband® (ABIN4886426). Tested in IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human ADAR1 recombinant protein (Position: S128-Q346). Human ADAR1 shares 90.2% and 50.7% amino acid (aa) sequence identity with mouse and rat ADAR1, respectively.
    亚型
    IgG
    Top Product
    Discover our top product ADAR Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    1. "Entrez Gene: ADAR Adenosine Deaminase Acting on RNA". 2. Kim U, Wang Y, Sanford T, Zeng Y, Nishikura K (November 1994). "Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing". Proceedings of the National Academy of Sciences of the United States of America 91 (24): 11457-61.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原
    ADAR (Adenosine Deaminase, RNA-Specific (ADAR))
    别名
    ADAR (ADAR 产品)
    背景

    Synonyms: Double-stranded RNA-specific adenosine deaminase,DRADA,3.5.4.37,136 kDa double-stranded RNA-binding protein,p136,Interferon-inducible protein 4,IFI-4,K88DSRBP,ADAR,ADAR1, DSRAD, G1P1, IFI4,

    Tissue Specificity: Ubiquitously expressed, highest levels were found in brain and lung. Isoform 5 is expressed at higher levels in astrocytomas as compared to normal brain tissue and expression increases strikingly with the severity of the tumor, being higher in the most aggressive tumors. .

    Background: Double-stranded RNA-specific adenosine deaminase, also known as ADAR1, is an enzyme that in humans is encoded by the ADAR gene. It is mapped to 1q21.3. This gene encodes the enzyme responsible for RNA editing by site-specific deamination of adenosines. This enzyme destabilizes double-stranded RNA through conversion of adenosine to inosine. Mutations in this gene have been associated with dyschromatosis symmetrica hereditaria. Alternative splicing results in multiple transcript variants.

    分子量
    110 kDa, 150 kDa
    基因ID
    103
    UniProt
    P55265
    途径
    Protein targeting to Nucleus
You are here:
Chat with us!