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ACADVL 抗体 (C-Term)

This anti-ACADVL antibody is a 兔 多克隆 antibody detecting ACADVL in WB, IHC, IF, ICC, IP 和 FACS. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN4886415
发货至: 中国

Quick Overview for ACADVL 抗体 (C-Term) (ABIN4886415)

抗原

See all ACADVL 抗体
ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This ACADVL antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Flow Cytometry (FACS)
  • 抗原表位

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    AA 538-576, C-Term

    原理

    Anti-ACADVL Antibody Picoband®

    序列

    RALEQFATVV EAKLIKHKKG IVNEQFLLQR LADGAIDLY

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    产品特性

    Anti-ACADVL Antibody Picoband® (ABIN4886415). Tested in Flow Cytometry, IP, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human ACADVL, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Immunoprecipitation, 0.5-2 μg/mL, Human
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
    1. Andresen BS, Olpin S, Poorthuis BJ, Scholte HR, Vianey-Saban C, Wanders R, Ijlst L, Morris A, Pourfarzam M, Bartlett K, Baumgartner ER, deKlerk JB, Schroeder LD, Corydon TJ, Lund H, Winter V, Bross P, Bolund L, Gregersen N (Feb 1999). "Clear correlation of genotype with disease phenotype in very-long-chain acyl-CoA dehydrogenase deficiency". American Journal of Human Genetics 64 (2): 479-94. 2. Strauss AW, Powell CK, Hale DE, Anderson MM, Ahuja A, Brackett JC, Sims HF (Nov 1995). "Molecular basis of human mitochondrial very-long-chain acyl-CoA dehydrogenase deficiency causing cardiomyopathy and sudden death in childhood". Proceedings of the National Academy of Sciences of the United States of America 92 (23): 10496-500.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    ACADVL (Acyl-CoA Dehydrogenase, Very Long Chain (ACADVL))

    别名

    ACADVL

    背景

    Synonyms: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial,VLCAD,1.3.8.9,ACADVL,VLCAD,

    Background: Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (VLCAD) is an enzyme that in humans is encoded by the ACADVL gene. The protein encoded by this gene is targeted to the inner mitochondrial membrane, where it catalyzes the first step of the mitochondrial fatty acid beta-oxidation pathway. This acyl-Coenzyme A dehydrogenaseis specific to long-chain and very-long-chain fatty acids. A deficiency in this gene product reduces myocardial fatty acid beta-oxidation and is associated with cardiomyopathy. Alternative splicing results in multiple transcript variants encoding different isoforms.

    分子量

    70 kDa

    基因ID

    37

    UniProt

    P49748

    途径

    ER-Nucleus Signaling, Monocarboxylic Acid Catabolic Process
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